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1-cyclohexyl-3-(4-iodophenyl)urea

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Identification
Molecular formula
C13H17IN2O
CAS number
58665-05-7
IUPAC name
1-cyclohexyl-3-(4-iodophenyl)urea
State
State

This compound is in a solid state at room temperature.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
340.50
Boiling point (Kelvin)
613.70
General information
Molecular weight
334.18g/mol
Molar mass
334.1840g/mol
Density
1.5000g/cm3
Appearence

1-Cyclohexyl-3-(4-iodophenyl)urea appears as a crystalline solid. It is typically white or off-white in color. The compound is not known to have any distinctive odors and due to its crystalline nature, it may reflect light to some degree.

Comment on solubility

Solubility of 1-cyclohexyl-3-(4-iodophenyl)urea

1-cyclohexyl-3-(4-iodophenyl)urea, with the chemical formula C13H17IN2O, presents intriguing solubility properties that can be influenced by its structural features. Here are some key points regarding its solubility:

  • Polar Characteristics: The presence of both the urea functional group and the iodine atom contributes to the **polarity** of the compound, potentially impacting its solubility in various solvents.
  • Solvent Preferences: Typically, compounds with urea linkages show increased solubility in polar solvents like water and methanol, yet the bulky cyclohexyl group may hinder complete solubility.
  • Hydrophobic Interactions: The cyclohexyl moiety imparts hydrophobic characteristics that may decrease solubility in polar solvents but enhance compatibility with non-polar solvents.
  • Temperature Dependence: Solubility often varies with temperature; thus, solubility trials at different temperatures would elucidate whether this compound exhibits increased solubility at elevated temperatures.

In summary, while predictions of solubility in specific solvents can be made based on structural analysis, empirical testing remains crucial. As with many compounds, a detailed solubility profile ensures a comprehensive understanding of its behavior in various environments.

Interesting facts

Interesting Facts about 1-Cyclohexyl-3-(4-Iodophenyl)urea

1-Cyclohexyl-3-(4-iodophenyl)urea is a fascinating compound that belongs to the class of urea derivatives. Here are some intriguing aspects:

  • Pharmacological Relevance: This compound has garnered attention in the pharmaceutical industry, particularly for its potential use in drug discovery and development.
  • Synthesis: The synthesis of 1-cyclohexyl-3-(4-iodophenyl)urea involves a multi-step process, typically starting from readily available starting materials. This often includes reactions such as amination and urea formation.
  • Mechanism of Action: Compounds like 1-cyclohexyl-3-(4-iodophenyl)urea may act on specific biological targets due to the presence of both the cyclohexyl and iodophenyl groups, which can enhance biological activity and specificity.
  • Structural Features: The compound's unique structure allows for diverse interactions with biological molecules. With the iodine atom, it can participate in halogen bonding, potentially influencing molecular interactions.
  • Research Applications: This compound has been studied in various research contexts, including studies related to cancer therapies and other disease mechanisms.

Furthermore, the combination of the cyclohexyl ring and the iodophenyl moiety presents unique opportunities for scientists to explore the compound's reactivity and application in various fields such as materials science and organic electronics. The versatility in its chemistry makes 1-cyclohexyl-3-(4-iodophenyl)urea a subject of ongoing interest in contemporary research.

Synonyms
n-cyclohexyl-n'-(4-iodophenyl)urea
1-cyclohexyl-3-(4-iodophenyl)urea
287185-29-9
CHEBI:41480
1-cyclohexyl-3-(p-iodophenyl)urea
N-cyclohexyl-N'-(p-iodophenyl)urea
CIU
1ek1
1vj5
SCHEMBL4319424
CHEMBL1231797
BDBM129304
HMS3604N07
STL069107
AKOS000497853
DB02029
NS00068446
US8815951, 53
AN-329/40291066
EN300-12912513
A1-43709
Q27093117
Z44596720