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Aliskiren

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Identification
Molecular formula
C30H53N3O6S
CAS number
173334-57-1
IUPAC name
1-carbamimidoyl-N-[[1-[3-hydroxy-2-(2-naphthylsulfonylamino)propanoyl]pyrrolidin-2-yl]methyl]piperidine-3-carboxamide
State
State

Aliskiren is typically solid at room temperature, provided in oral tablet form for pharmaceutical use.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
551.77g/mol
Molar mass
551.7690g/mol
Density
1.2580g/cm3
Appearence

Aliskiren, in its pure form, is a white to slightly yellowish powder. It is often found in tablet form when used as a medication.

Comment on solubility

Solubility of 1-carbamimidoyl-N-[[1-[3-hydroxy-2-(2-naphthylsulfonylamino)propanoyl]pyrrolidin-2-yl]methyl]piperidine-3-carboxamide

The solubility of the compound 1-carbamimidoyl-N-[[1-[3-hydroxy-2-(2-naphthylsulfonylamino)propanoyl]pyrrolidin-2-yl]methyl]piperidine-3-carboxamide, with the chemical formula C30H53N3O6S, is of great interest due to its unique structural characteristics.

This compound has potential implications in various applications, and understanding its solubility is crucial. Some points to consider are:

  • Hydrophobic vs. Hydrophilic: With a significant presence of hydrocarbon chains, the compound may exhibit hydrophobic characteristics, making it less soluble in water.
  • Solvent Compatibility: The presence of both polar and non-polar groups suggests that it might dissolve better in organic solvents rather than in aqueous solutions.
  • Temperature Dependency: The solubility can vary with temperature; hence, it might be beneficial to assess how solubility changes with increasing temperatures.
  • pH Influence: Variation in pH may also affect the solubility, especially due to the amino and carboxamide functional groups present in the compound.

As a general observation, assessing the solubility characteristics of complex molecules like this can often reveal critical insights into their behavior in biological systems as well as their potential for use in pharmaceuticals.

In conclusion, while the specific solubility of this compound may not be widely documented, its intricate structure suggests a fascinating interplay between various solvation dynamics. Understanding these dynamics is essential for optimizing its applications.

Interesting facts

Interesting Facts about 1-Carbamimidoyl-N-[[1-[3-Hydroxy-2-(2-Naphthylsulfonylamino)propanoyl]pyrrolidin-2-yl]methyl]piperidine-3-carboxamide

This compound, an intriguing example of modern chemical synthesis, showcases the power of structure-activity relationships in medicinal chemistry. Here are some remarkable insights:

  • Medicinal Chemistry: The compound's complex structure suggests potential activity in pharmaceutical applications, especially in targeting specific biological pathways.
  • Multi-Functional Moieties: Its design incorporates several functional groups, such as a piperidine ring and a naphthyl sulfonyl group, which may contribute to its interaction with biological targets.
  • Targeting Cancer: With parts of its structure tailored for binding to enzyme active sites, this compound may play a role in the development of novel anti-cancer therapies.
  • Research Potential: Due to its unique features, this compound is a subject of investigation in various research fields, such as medicinal chemistry and pharmacology.
  • Analytical Studies: The complexity of the compound provides an excellent candidate for studies involving advanced characterization techniques, including nuclear magnetic resonance (NMR) and mass spectrometry.

As scientists delve deeper into the structure and functionality of this compound, it's fascinating to consider the profound impact it could have on drug design and therapeutic strategies. Its exploratory nature reflects the continuous evolution of chemical innovation and the pursuit of new medicinal agents.

Synonyms
SCHEMBL8154518