Interesting facts
Interesting Facts about 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine
1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine is a fascinating compound that showcases the intricacies of organic chemistry. This compound, primarily studied in the context of medicinal chemistry, is noteworthy for several reasons:
- Aromatic Complexity: The presence of multiple aromatic rings, including bis(4-fluorophenyl) groups and a trimethoxyphenyl moiety, highlights the compound's potential for unique interactions and biological activity.
- Fluorine Substitution: The incorporation of fluorine atoms is a common strategy in drug design, often enhancing the chemical stability and bioavailability of compounds. In this case, the 4-fluorophenyl groups may contribute to the compound’s pharmacological properties.
- Piperazine Ring: The piperazine scaffold is known for its versatility in the pharmaceutical industry. Compounds featuring this ring often exhibit activities such as antidepressant, anxiolytic, and anti-inflammatory effects.
- Potential Uses: Ongoing research may explore its utility in treating various diseases, especially in the realm of psychiatric disorders, due to its ability to modulate neurotransmitter systems.
- Synthesis and Reactions: The synthesis of such a complex organic molecule involves numerous steps, often requiring specialized techniques in organic synthesis to introduce the desired functional groups with precision.
In summary, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine serves as an example of how modifications at the molecular level can lead to compounds with distinct potential therapeutic applications. It illustrates the balance between structure and function that defines the field of medicinal chemistry.
Synonyms
lomerizine
101477-55-8
Lomerizine [INN]
1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine
lomerizina
Lomerazine
UNII-DEE37CY4VO
Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-
DEE37CY4VO
LOMERIZINE [MI]
LOMERIZINE [WHO-DD]
CHEMBL29188
DTXSID6048387
1-(Bis(p-fluorophenyl)-methyl)-4-(2,3,4-trimethoxybenzyl)piperazine
1-(Bis(p-fluorophenyl)methyl)-4-(2,3,4-trimethoxybenzyl)piperazine
NCGC00164543-01
iomerizine
lomerizinum
1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine
1-(2,3,4-trimethoxybenzyl)-4-[bis(4-fluorophenyl)methyl]piperazine
1-(bis(4-fluorophenyl)methyl)-4-((2,3,4-trimethoxyphenyl)methyl)piperazine
Oprea1_445487
SCHEMBL79390
DTXCID1028360
CHEBI:94682
JQSAYKKFZOSZGJ-UHFFFAOYSA-N
HMS2090A21
HMS3264O04
HY-B0768
BDBM50095765
DL-244
AKOS015895327
AT37184
CCG-213815
DB14065
NCGC00164543-04
FF137441
CS-0009657
NS00071599
AB00003587-01
AB00003587-09
AB00003587-11
AB00003587_12
AB00003587_13
EN300-18414867
SR-01000763880
Q6669453
SR-01000763880-3
BRD-K62858456-001-01-8
BRD-K62858456-300-01-4
Z164035568
1-(bis(4-fluorophenyl)methyl)-4-(2,3,4-trimethoxybenzyl)piperazine
1-[Bis-(4-fluoro-phenyl)-methyl]-4-(2,3,4-trimethoxy-benzyl)-piperazine(Lomerizine)
Solubility of 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine
The solubility of the compound 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine (C17H18F3NO) can be influenced by several factors due to its unique structure.
Generally, the solubility characteristics can be summarized as follows:
In conclusion, while definitive solubility data may be necessary to fully understand the behavior of this compound in various solvents, it is clear that the interplay of its polar and nonpolar components plays a critical role in determining its solubility profile. As such, further experimental investigation may provide valuable insights into its practical applications.