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1-benzyl-3-(4-methoxyphenyl)sulfonyl-6-oxo-hexahydropyrimidine-4-carbohydroxamic acid

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Identification
Molecular formula
C19H21N3O6S
CAS number
Not available
IUPAC name
1-benzyl-3-(4-methoxyphenyl)sulfonyl-6-oxo-hexahydropyrimidine-4-carbohydroxamic acid
State
State
At room temperature, this compound is solid. It is stable under normal conditions but may require appropriate storage to maintain its integrity.
Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
391.45g/mol
Molar mass
391.4400g/mol
Density
1.3000g/cm3
Appearence

The compound 1-benzyl-3-(4-methoxyphenyl)sulfonyl-6-oxo-hexahydropyrimidine-4-carbohydroxamic acid typically appears as a crystalline solid. The appearance is often a white to off-white powder, although it can vary slightly depending on purity and specific sample conditions.

Comment on solubility

Solubility of 1-benzyl-3-(4-methoxyphenyl)sulfonyl-6-oxo-hexahydropyrimidine-4-carbohydroxamic acid

The solubility of the compound 1-benzyl-3-(4-methoxyphenyl)sulfonyl-6-oxo-hexahydropyrimidine-4-carbohydroxamic acid (C19H21N3O6S) is influenced by its complex molecular structure, which consists of both hydrophobic and hydrophilic components. The presence of the sulfonyl group and hydroxamic acid functional groups plays a crucial role in determining its solubility profile.

Key Factors Affecting Solubility:

  • Polarity: The hydroxamic acid portion tends to increase polarity, suggesting potential solubility in polar solvents, such as water.
  • Hydrophobic Interactions: The benzyl and methoxyphenyl substituents contribute hydrophobic characteristics that may hinder solubility in aqueous environments.
  • pH Dependency: As a hydroxamic acid, the solubility may vary with pH changes, often being higher in basic conditions where the acid group is deprotonated.

In summary, the overall solubility of this compound can be described as moderate in polar solvents and potentially limited in nonpolar environments. This dual nature illustrates the complexity of predicting solubility based on molecular architecture, making experimental solubility determinations essential for practical applications.

Interesting facts

Interesting Facts about 1-benzyl-3-(4-methoxyphenyl)sulfonyl-6-oxo-hexahydropyrimidine-4-carbohydroxamic acid

This intriguing compound, known as 1-benzyl-3-(4-methoxyphenyl)sulfonyl-6-oxo-hexahydropyrimidine-4-carbohydroxamic acid, showcases a unique structural composition that suggests potential biological activities. Here are some fascinating aspects to note:

  • Diverse Functional Groups: The presence of a sulfonyl group, a hydroxamic acid moiety, and a ketone highlights its versatility. This combination can influence the compound's reactivity and interactions with biological targets.
  • Potential Biological Applications: Compounds with hydroxamic acid structures are often studied for their roles as enzyme inhibitors. They have been researched for anti-cancer, anti-inflammatory, and antibacterial properties, hinting at the therapeutic potential of this specific compound.
  • Chemical Stability: The hexahydropyrimidine ring lends stability, which is critical in drug design. Stability in a compound can often correlate with improved bioavailability and efficacy in biological systems.
  • Substituent effects: The methoxy group on the phenyl ring may enhance lipophilicity, potentially affecting how the compound interacts biologically, contributing to its mechanism of action.

As researchers delve into compounds like this, they contribute to a deeper understanding of medicinal chemistry and the development of new therapeutic agents. The study of such compounds is essential, as it can lead to significant advancements in pharmaceutical science.

In the words of chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Exploring complex compounds like this one exemplifies the creativity and innovation inherent in the field of chemistry.

Synonyms
CHEMBL437017
SCHEMBL4312415
BDBM50608588
PD040147