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1-Benzhydryl-4-cinnamyl-piperazine

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Identification
Molecular formula
C26H28N2
CAS number
129580-63-8
IUPAC name
1-benzhydryl-4-cinnamyl-piperazine
State
State

At room temperature, 1-benzhydryl-4-cinnamyl-piperazine is in a solid state. It is stable under typical storage conditions and should be kept in an airtight container to prevent it from adsorbing moisture or reactive gases from the environment.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.20
Boiling point (Celsius)
511.20
Boiling point (Kelvin)
784.40
General information
Molecular weight
398.53g/mol
Molar mass
398.5560g/mol
Density
1.1200g/cm3
Appearence

1-Benzhydryl-4-cinnamyl-piperazine typically appears as a white to off-white crystalline powder. The compound is characterized by a slight to moderate aromatic odor, owing to its piperazine and cinnamyl functional groups.

Comment on solubility

Solubility of 1-benzhydryl-4-cinnamyl-piperazine

The solubility of 1-benzhydryl-4-cinnamyl-piperazine (C26H28N2) is influenced by its chemical structure and molecular characteristics. Understanding the solubility of this compound provides insights into its behavior in various environments and potential applications. Here are key points regarding its solubility:

  • Polar vs. Non-Polar Solvents: 1-benzhydryl-4-cinnamyl-piperazine is expected to be more soluble in organic solvents due to its relatively hydrophobic nature from the presence of aromatic rings and alkyl groups.
  • Hydrogen Bonding: The nitrogen atoms in the piperazine ring can engage in hydrogen bonding, which may allow for some degree of solubility in polar solvents, depending on the conditions.
  • Influence of Temperature: Solubility often increases with temperature, so higher temperatures may enhance the dissolution rate of this compound in suitable solvents.
  • Application of pH: The solubility might also vary depending on the pH of the solution, as changes can affect the protonation state of the nitrogen atoms.

In conclusion, while direct solubility data might not be extensively documented for this specific compound, its solubility is likely to be influenced by a combination of its molecular interactions and the nature of the solvent used. As a guideline, always consider the solvent type, temperature, and pH conditions when evaluating the solubility of 1-benzhydryl-4-cinnamyl-piperazine.

Interesting facts

Interesting Facts about 1-benzhydryl-4-cinnamyl-piperazine

1-benzhydryl-4-cinnamyl-piperazine is a fascinating compound that blends the structural elements of piperazine—a cyclic compound known for its versatility—and aromatic substitutions that enhance its biological properties. Here are some intriguing insights into this compound:

  • Versatile Chemistry: The presence of a piperazine ring makes this compound a valuable template in medicinal chemistry, often utilized in the development of numerous pharmaceuticals.
  • Biological Activity: Compounds with piperazine moieties are frequently studied for their potential as antipsychotic agents and have also shown efficacy in treating other neurological disorders.
  • Aromatic Substituents: The incorporation of aromatic groups, such as benzhydryl and cinnamyl, can lead to enhanced activity and selectivity toward certain biological targets, making this compound a candidate for further research.
  • Drug Development: Due to its complex structure, 1-benzhydryl-4-cinnamyl-piperazine serves as an important model for studying structure-activity relationships in drug design.
  • Enhanced Stability: The diverse substituents can also affect the compound's stability, pharmacokinetics, and bioavailability, crucial aspects when considering therapeutic applications.

Overall, 1-benzhydryl-4-cinnamyl-piperazine not only stands out for its intriguing structure but also paves the way for innovations in drug discovery. As scientists continue to explore its properties, this compound holds the promise of revealing new therapeutic avenues that could transform the landscape of medicinal chemistry.

Synonyms
1-(diphenylmethyl)-4-(3-phenylprop-2-enyl)piperazine
Prestwick0_000278
Prestwick1_000278
1-benzhydryl-4-(3-phenylprop-2-enyl)piperazine
Oprea1_696883
SPBio_002375
HMS3372L16
1-Cinnamyl-4-diphenylmethylpiperazine
DB00568
DB-047662
C3459
Q27224950
1-(diphenylmethyl)-4-(3-phenyl-2-propenyl) piperazine