Skip to main content

1-benzhydryl-4-(3-phenylprop-1-enyl)piperazine

ADVERTISEMENT
Identification
Molecular formula
C25H28N2
CAS number
130249-79-1
IUPAC name
1-benzhydryl-4-(3-phenylprop-1-enyl)piperazine
State
State

This compound is usually found in solid state at room temperature.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.10
Boiling point (Celsius)
458.50
Boiling point (Kelvin)
731.70
General information
Molecular weight
374.52g/mol
Molar mass
374.5400g/mol
Density
1.1000g/cm3
Appearence

The compound is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 1-benzhydryl-4-(3-phenylprop-1-enyl)piperazine

The solubility of 1-benzhydryl-4-(3-phenylprop-1-enyl)piperazine (C25H28N2) exhibits some interesting characteristics due to its unique molecular structure. Several factors can influence its solubility:

  • Polarity: Given the presence of both nonpolar aromatic rings and polar amine groups, the compound may have moderate solubility in organic solvents.
  • Hydrogen bonding: The potential for hydrogen bonding with polar solvents may enhance solubility in certain cases.
  • Solvent compatibility: It is likely to be more soluble in nonpolar solvents like dichloromethane or ethanol rather than in water, due to its hydrophobic regions.

In general, compounds with larger hydrophobic portions tend to have lower solubility in polar solvents, which can lead to varying outcomes depending on the solvent used. As one might say, "like dissolves like." Therefore, predicting the specific solubility of this compound would require experimental data in various solvents.

In summary, while the exact solubility can vary, it is essential to consider the compound's polarity and hydrogen bonding capacity when determining its behavior in different solvent environments.

Interesting facts

Interesting Facts about 1-benzhydryl-4-(3-phenylprop-1-enyl)piperazine

1-benzhydryl-4-(3-phenylprop-1-enyl)piperazine is a fascinating compound that showcases the versatility of piperazine derivatives in medicinal chemistry. Here are some intriguing points to consider:

  • Structure and Stability: The compound features a unique structure where the piperazine ring is substituted with a benzhydryl and a phenylprop-1-enyl group, contributing to its distinct properties.
  • Medicinal Applications: Piperazine derivatives are known for their therapeutic potential. They have been explored for use in a variety of pharmacological applications, including but not limited to antidepressant and anxiolytic activities.
  • Complex Synthesis: The synthesis of 1-benzhydryl-4-(3-phenylprop-1-enyl)piperazine may involve complex multistep reactions, often requiring advanced techniques in organic synthesis, which showcases the skill and creativity of chemists.
  • Binding Affinity: Understanding the interactions of this compound with biological targets could help in elucidating its mechanism of action. Research into its binding affinity with specific receptors can uncover potential pathways for therapeutic use.
  • Structure-Activity Relationship (SAR): Studying SAR for 1-benzhydryl-4-(3-phenylprop-1-enyl)piperazine could pave the way for the development of more effective analogs, tailoring modifications to enhance specific interactions or reduce adverse effects.

Overall, this compound not only represents a class of compounds that hold promise in drug development but also exemplifies the intricacies involved in synthetic organic chemistry. Understanding such compounds can lead to innovative solutions in the field of pharmaceuticals.

Synonyms
Spectrum_001438
Spectrum2_001531
Spectrum3_000670
Spectrum4_001076
KBioGR_001432
KBioSS_001918
DivK1c_000788
SPBio_001342
SCHEMBL16226133
KBio1_000788
KBio2_001918
KBio2_004486
KBio2_007054
KBio3_001559
NINDS_000788
1-(diphenylmethyl)-4-(3-phenylprop-1-enyl)piperazine
Q27188699