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1-Aminocyclopentanecarboxylic acid

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Identification
Molecular formula
C6H11NO2
CAS number
16534-50-2
IUPAC name
1-aminocyclopentanecarboxylic acid
State
State

At room temperature, 1-Aminocyclopentanecarboxylic acid is typically in a solid state.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
129.17g/mol
Molar mass
129.1680g/mol
Density
1.2400g/cm3
Appearence

1-Aminocyclopentanecarboxylic acid appears as a white crystalline powder which is often used in research applications. It is known for its stability and ability to be dissolved in a variety of solvents, typically resulting in a colorless solution.

Comment on solubility

Solubility of 1-Aminocyclopentanecarboxylic Acid

1-aminocyclopentanecarboxylic acid (C6H11NO2) exhibits interesting solubility characteristics that can be attributed to its molecular structure.

Factors Influencing Solubility

The solubility of this compound is influenced by several key factors:

  • Polarity: The presence of the amino group (-NH2) and carboxylic acid group (-COOH) contributes to its polar nature, enhancing its solubility in polar solvents, such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules allows for increased solubility in aqueous environments.
  • Molecular Size: Being a small organic molecule, it generally allows for better interaction with solvent molecules.

Solubility in Various Solvents

1-aminocyclopentanecarboxylic acid is expected to be:

  • Highly soluble in water due to its polar functionality.
  • Less soluble in non-polar solvents, such as hexane or toluene, due to insufficient interactions.

In summary, the solubility of 1-aminocyclopentanecarboxylic acid is characterized by its strong interaction capabilities with polar solvents, making it an interesting compound for various applications in chemical research and industries where solubility plays a critical role.

Interesting facts

Interesting Facts about 1-Aminocyclopentanecarboxylic Acid

1-Aminocyclopentanecarboxylic acid, often abbreviated as ACPC, is a fascinating compound in the realm of organic chemistry due to its unique structure and potential applications. Below are some intriguing aspects of this compound:

  • Structural Uniqueness: ACPC features a cyclopentane ring, which makes it a cyclic amino acid. The incorporation of an amino group and a carboxylic acid moiety on the same molecule presents unique steric and electronic properties.
  • Physiological Relevance: Compounds that resemble the structure of amino acids are often involved in biological processes, and ACPC has been studied for its potential roles in metabolism and neurotransmission.
  • Advantages in Peptide Synthesis: ACPC can be used as a building block in the synthesis of cyclic peptides, which are known for their stability and bioactivity, making them candidates for drug development.
  • Research Potential: The compound's ability to act as an inhibitor for certain enzymes has intrigued scientists aiming to discover new pharmacological agents, especially in treating neurological disorders.
  • Chirality: Being an amino acid derivative, ACPC exists in both L and D forms, which may confer different biological activities. This chirality is a significant factor in drug design and development.

As quoted by renowned chemist Linus Pauling, "The structure of a substance is its destiny," and this holds true for 1-aminocyclopentanecarboxylic acid. Its distinctive structure not only signifies its function in biological systems but also opens doors to novel synthetic applications in medicinal chemistry.

This compound shines as a prime example of how a small change in molecular structure can lead to vastly different properties and uses, making it an intriguing subject for ongoing research and exploration in the field of organic chemistry.

Synonyms
cycloleucine
52-52-8
1-Aminocyclopentanecarboxylic acid
1-Aminocyclopentane-1-carboxylic acid
Cycloleucin
1-Amino-1-cyclopentanecarboxylic acid
1-Amino-1-carboxycyclopentane
CYCLO-LEUCINE
1-Amino-cyclopentanecarboxylic acid
Cyclopentanecarboxylic acid, 1-amino-
NSC 1026
CB 1639
1-Aminocyclopentanecarboxylate
X 201
HSDB 5195
NSC1026
WR 14,997
EINECS 200-144-6
UNII-0TQU7668EI
MFCD00001381
aminocyclopentanecarboxylic acid
BRN 0636626
0TQU7668EI
CHEBI:40547
AI3-26442
Cyclopentanecarboxylic acid, 1-amino-, L-
NSC-1026
Cycloleucine1-Amino-cyclopentanecarboxylic acid
CYCLOLEUCINE [MI]
CYCLOLEUCINE [HSDB]
1-amino-1-cyclopentane carboxylic acid
WR 14997
CHEMBL295830
Acid, aminocyclopentanecarboxylic
DTXSID5024475
NILQLFBWTXNUOE-UHFFFAOYSA-
1 Aminocyclopentanecarboxylic acid
1-amino-1-Cyclopentanecarboxylate
1-aminocyclopentane-1-carboxylate
Acid, 1-aminocyclopentanecarboxylic
4-14-00-00974 (Beilstein Handbook Reference)
CB-1639
1-amino cyclopentane carboxylic acid
1-ammonio-1-cyclopentanecarboxylate
A829129
Leucine, Cyclo-
1-aminocyclopentane
1-Aminocyclopentane carboxylic acid
Amino-1-cyclopentanecarboxylic acid
Cycloleucine, 97%
(2E)-Decenoyl-ACP
Spectrum_001268
1y1m
H-NH(1)cPen-OH
AC1OCG3T
Spectrum2_000931
Spectrum3_001514
Spectrum4_000340
Spectrum5_001136
Biomol-NT_000201
NCIMech_000677
WLN: L5TJ AZ AVQ
SCHEMBL8495
BSPBio_003187
CYCLOLEUCIN [WHO-DD]
KBioGR_000719
KBioSS_001748
DivK1c_000723
SPECTRUM1502128
SPBio_000862
1-amino-Cyclopentanecarboxylate
BPBio1_001084
DTXCID304475
1aminocyclopentanecarboxylic acid
Cyclopentanecarboxylic acid, L-
1-Aminocyclopentanecarboxylicacid
HMS502E05
KBio1_000723
KBio2_001748
KBio2_004316
KBio2_006884
KBio3_002687
1Aminocyclopentane1carboxylic acid
NINDS_000723
HMS1921L08
Cyclopentanecarboxylic acid, 1amino
ALBB-035361
CS-B0093
1-amino-cyclopentane carboxylic acid
1026, NSC
BBL020454
BDBM50070638
CCG-35835
FD1031
STK133034
ZINC00001234
AKOS000183252
AC-2700
DB04620
IDI1_000723
NCGC00094966-01
NCGC00094966-02
NCGC00094966-03
NCGC00094966-04
NCGC00163268-01
NCGC00178218-01
AC5
AS-11677
HY-30008
NCI60_000070
SY002601
Cycloleucine1-amino-cyclopentanecarboxylate
CYCLOPENTANECARBOXYLIC ACID, L-AMINO
DB-031284
A1063
NS00032521
EN300-39470
1-Aminocyclopentanecarboxylic acid;Cyclolencine
A19400
C03969
Q607775
F8881-4536
Z234896477
3DD7E30B-2149-43D9-A44B-7A59D546A28B