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1-aminocyclobutane-1,3-dicarboxylic acid

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Identification
Molecular formula
C6H9NO4
CAS number
222920-55-6
IUPAC name
1-aminocyclobutane-1,3-dicarboxylic acid
State
State

At room temperature, 1-aminocyclobutane-1,3-dicarboxylic acid is in a solid state. It forms part of the structured organic compounds that exhibit stability at moderate environmental temperatures.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
216.00
Boiling point (Kelvin)
489.15
General information
Molecular weight
157.15g/mol
Molar mass
157.1540g/mol
Density
1.4850g/cm3
Appearence

1-Aminocyclobutane-1,3-dicarboxylic acid typically appears as a solid under standard conditions. It is usually in the crystalline form.

Comment on solubility

Solubility of 1-aminocyclobutane-1,3-dicarboxylic acid

1-aminocyclobutane-1,3-dicarboxylic acid (C6H9NO4) exhibits interesting solubility characteristics that can be influenced by various factors. Here are some key points regarding its solubility:

  • Polar Nature: The presence of carboxylic acid groups (-COOH) in the structure enhances its polar nature, contributing to its solubility in polar solvents, most notably water.
  • Hydrophilic Interactions: The ability of the compound to form hydrogen bonds with water molecules increases its solubility. The amino group (-NH2) also aids in solvation, making it more soluble in aqueous solutions.
  • Temperature Dependence: As with many organic acids, the solubility of 1-aminocyclobutane-1,3-dicarboxylic acid can be affected by temperature. Higher temperatures generally increase solubility.
  • pH Sensitivity: As a dicarboxylic acid, its solubility may vary significantly with changes in pH, where the protonation state of the carboxylic groups can influence the overall solubility in different pH environments.

In conclusion, 1-aminocyclobutane-1,3-dicarboxylic acid is expected to be highly soluble in water due to its polar functional groups, while its solubility profile may vary based on temperature and pH conditions. As with many organic compounds, understanding these factors is essential for predicting its behavior in various chemical environments.

Interesting facts

Interesting Facts about 1-Aminocyclobutane-1,3-dicarboxylic Acid

1-Aminocyclobutane-1,3-dicarboxylic acid is a fascinating compound that belongs to the class of amino acids derivatives. Here are some intriguing insights:

  • Cyclic Structure: This compound features a unique cyclobutane ring, which is a four-membered ring. Its strained structure makes it particularly interesting for studying the effects of ring strain on reactivity and stability.
  • Versatile Functional Groups: The presence of two carboxylic acid groups in this compound allows for various chemical reactions. These functional groups can engage in decarboxylation, esterification, and other transformations that are essential in organic synthesis.
  • Biological Importance: As an amino acid derivative, 1-aminocyclobutane-1,3-dicarboxylic acid is of interest in biochemistry. Amino acids are the building blocks of proteins, and studying such derivatives can provide insights into new pathways for enzymatic reactions or protein interactions.
  • Research Applications: This compound may be utilized in the development of pharmaceuticals and agrochemicals, particularly in the design of novel bioactive molecules that can mimic natural compounds in biological systems.
  • Potential for Peptide Synthesis: The presence of both amine and carboxylic acid functionalities facilitates the formation of peptides, which are vital compounds in biological processes and drug design.

In summary, 1-aminocyclobutane-1,3-dicarboxylic acid stands out due to its unique structural properties and the breadth of potential applications in both chemistry and biology. Its continued study is essential for uncovering new insights and applications in scientific research.

Synonyms
73550-55-7
117488-23-0
cis-ABCD
1-aminocyclobutane-1,3-dicarboxylic acid
CIS-ACBD
trans-ABCD
Trans-acbd
Trans-1-aminocyclobutane-1,3-dicarboxylic acid
CIS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
2,4-Methanoglutamate
164225-42-7
(1s,3s)-1-Aminocyclobutane-1,3-dicarboxylic acid
1-Aminocyclobutane-cis-1,3-dicarboxylic acid
cis-2,4-methanoglutamate
(1R,3R)-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
1,3-Cyclobutanedicarboxylic acid, 1-amino-, cis-
1,3-Cyclobutanedicarboxylicacid,1-amino-(9CI)
2,4-methanoglutamic acid
cis-1-Amino-1,3-cyclobutanedicarboxylic acid
JEG
cis-1-Aminocyclobutane-1,3-dicarboxylic acid hydrate
NSC621814
trans-1-Aminocyclobutane-1,3-dicarboxylic acid hydrate
Tocris-0271
1,3-Cyclobutanedicarboxylic acid, 1-amino-, cis-, hydrate
Biomol-NT_000172
1-aminocyclobutane-trans-1,3-dicarboxylic acid
BPBio1_001136
SCHEMBL1063416
SCHEMBL1064244
SCHEMBL1263461
SCHEMBL7530916
CHEMBL1316912
CHEMBL1437288
CHEMBL1555263
DTXSID60922431
1,3-Cyclobutanedicarboxylic acid, 1-amino-, trans-, hydrate
DTXSID601312880
GLXC-10047
HMS3266E13
BCP18258
BCP18259
AKOS006230090
AKOS006239508
AKOS006239813
AB86481
AB86519
HY-100616A
NSC-621814
NCGC00024521-01
NCGC00024521-02
NCGC00024521-03
NCGC00024521-04
NCGC00092272-01
NCGC00163685-01
1-Amino-1,3-cyclobutanedicarboxylic acid
DA-51932
PD065319
TS-08800
TS-08802
DB-041374
DB-126828
HY-100616
CS-0019789
EN300-63952
EN300-144924
EN300-296162
SR-01000597724
Cis-1-amino-cyclobutane-1,4-Methanoglutamic acid)
CIS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLICACID
SR-01000597724-1
1-AMINOCYCLOBUTANE-CIS -1,3-DICARBOXYLIC ACID
Q27461686
Z1270392248
trans-1-Aminocyclobutane-1,3-dicarboxylic acid; trans ACBD; transACBD
631-436-5