Skip to main content

Cimetidine

ADVERTISEMENT
Identification
Molecular formula
C10H16N6ClS
CAS number
51481-61-9
IUPAC name
1-[amino-(4-chloroanilino)methylene]-2-isopropyl-guanidine
State
State

At room temperature, cimetidine is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.15
Boiling point (Celsius)
538.70
Boiling point (Kelvin)
811.85
General information
Molecular weight
252.35g/mol
Molar mass
252.3480g/mol
Density
1.0600g/cm3
Appearence

Cimetidine is typically a white to off-white crystalline powder. It is very slightly soluble in water and has a characteristic odor.

Comment on solubility

Solubility of 1-[amino-(4-chloroanilino)methylene]-2-isopropyl-guanidine

The solubility of the compound 1-[amino-(4-chloroanilino)methylene]-2-isopropyl-guanidine (C10H16N6ClS) can be quite intriguing due to its unique structure.

Factors Influencing Solubility

Several factors might affect the solubility of this compound:

  • Polarity: The presence of multiple functional groups in the structure can enhance or restrict polar interactions with solvents.
  • Ionic Character: The Chlorine atom contributes to ionic interactions, which may affect solubility in water versus organic solvents.
  • Hydrogen Bonding: The amine groups could potentially form hydrogen bonds, impacting solubility in polar solvents.

Expected Solubility

Given its molecular structure, one might observe:

  • The compound may have moderate solubility in polar solvents such as water, due to the presence of amino groups.
  • It is likely more soluble in organic solvents than in aqueous solutions, particularly due to its bulky isopropyl side group.
  • Various sulfur-containing substituents can also contribute to unique solvation characteristics.

In summary, while specific solubility data can vary, understanding the molecular characteristics and interactions can provide insightful predictions regarding the solubility behavior of 1-[amino-(4-chloroanilino)methylene]-2-isopropyl-guanidine.

Interesting facts

Interesting Facts about 1-[amino-(4-chloroanilino)methylene]-2-isopropyl-guanidine

1-[amino-(4-chloroanilino)methylene]-2-isopropyl-guanidine is a fascinating compound with unique chemical properties and potential applications, particularly in the field of medicinal chemistry. Here are some intriguing aspects of this compound:

  • Biological Activity: This compound may possess significant biological activity due to its guanidine structure, which is often associated with various pharmacological effects.
  • Potential Drug Development: The presence of the 4-chloroaniline moiety suggests the compound might be explored for its use in anti-cancer or anti-inflammatory drugs, given that similar structures have been shown to exhibit such effects.
  • Structure-Activity Relationship: The isopropyl group can influence the compound's lipophilicity, potentially impacting its bioavailability and interaction with biological targets.
  • Research Interest: Compounds like this are often of great interest in research labs focusing on developing selective and potent therapeutics; understanding their mechanisms can reveal ways to combat various diseases.
  • Analytical Techniques: Understanding the structure and behavior of this compound can involve different analytical techniques such as NMR spectroscopy, mass spectrometry, and X-ray crystallography.

As a compound enriched with nitrogen atoms, it gives rise to a diverse range of bonding possibilities, making it a prime candidate for synthesis and exploration in the expansive field of organic chemistry. The synthetic routes to obtain this compound and its derivatives can lead to even more intriguing variations, opening doors for innovative discoveries.

As researchers delve deeper, they may find that this compound serves as a vital building block in the design of new therapeutics, emphasizing the importance of continued exploration in chemical science. Who knows what future studies could unveil about this exciting compound and its potential contributions to science and medicine?

Synonyms
500-92-5
(1E)-1-[amino-(4-chloroanilino)methylidene]-2-propan-2-ylguanidine
N1-(4-Chlorophenyl)-N5-isopropylbiguanide
DTXSID3022794
Proguanil?
MFCD00866201
GTPL9676
1-[amino-(4-chloroanilino)methylidene]-2-propan-2-ylguanidine
AC2030
FP41719
NCGC00016528-06
SY047103
DB-109846
NS00006951
diguanide, N^2-(4-chlorophenyl)-N-isopropyl-
Q420607
1-(4-chlorophenyl)-2-(N'-propan-2-ylcarbamimidoyl) guanidine
N1-(4-Chlorophenyl)-N5-isopropylbiguanide;N-(4-Chlorophenyl)-N'-isopropylimidodicarbonimidic diamide