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Didanosine

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Identification
Molecular formula
C10H12N4O3
CAS number
69655-05-6
IUPAC name
1-[9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]purin-6-yl]-1-hydroxy-guanidine
State
State

At room temperature, didanosine is typically found in a solid state. In pharmaceutical preparations, it is often found as an enteric-coated tablet or in aqueous solution form to enhance stability and absorption.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
236.23g/mol
Molar mass
236.2300g/mol
Density
1.6400g/cm3
Appearence

Didanosine typically appears as a white crystalline powder, which is highly soluble in water. When in solid form, the appearance is consistent with many pharmaceuticals as it is often processed into tablet form for medicinal use.

Comment on solubility

Solubility of 1-[9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]purin-6-yl]-1-hydroxy-guanidine

This compound, with the chemical formula C10H12N4O3, exhibits interesting solubility characteristics that can be crucial for its application in various fields. Understanding its solubility behavior can provide valuable insights into its potential uses:

  • Solvent Compatibility: The presence of multiple hydroxyl groups suggests a potential for good solubility in polar solvents, such as water or ethanol. This is indicative of the compound's ability to interact favorably with such solvents due to hydrogen bonding.
  • Electrical Charge: The guanidine moiety introduces a basic character which may influence solubility depending on the pH of the solution, allowing for possible ionization in alkaline conditions.
  • Crystallinity: If the compound possesses a high degree of crystallinity, this may hinder solubility in certain solvents, indicating that a balance must be reached between its structure and the medium it is placed in.
  • Temperature Influence: Typically, increasing temperature enhances solubility for many organic compounds, which might also apply here, allowing for a systematic approach to solubility testing.

In summary, the solubility of 1-[9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]purin-6-yl]-1-hydroxy-guanidine depends on several factors, including the choice of solvent, the pH environment, and temperature. Careful examination of these parameters can lead to a comprehensive understanding of how to effectively utilize this compound in various applications.

Interesting facts

Interesting Facts about 1-[9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]purin-6-yl]-1-hydroxy-guanidine

This unique compound, often referred to within scientific circles due to its complex structure, possesses intriguing characteristics that extend its significance beyond mere molecular composition.

Key Highlights:

  • Biological Relevance: This compound has garnered attention for its potential applications in biotechnology and pharmacology. Its structure suggests interactions with biological systems that could lead to therapeutic developments.
  • Structural Complexity: The presence of both a purine and a hydroxymethyl-tetrahydrofuran moiety illustrates the compound's intricate architecture, making it a focus of research aimed at synthesizing novel drugs.
  • Stability Considerations: The guanidine group in this compound may influence its hydrolytic stability, impacting how the compound behaves under physiological conditions.
  • Research Applications: Scientists are exploring its role as a potential modulator of enzymatic processes, particularly those related to nucleic acids, which could unveil new avenues in gene therapy or enzyme inhibition strategies.

In the words of renowned chemist Linus Pauling, "Science is not only compatible with spirituality; it is a profound source of spirituality." This sentiment resonates particularly well with the investigation of compounds such as this, as researchers delve into the microcosm of molecular interactions and their larger implications in health and medicine.

Overall, 1-[9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]purin-6-yl]-1-hydroxy-guanidine serves as a reminder of the intricate connections between molecular structure and biological function, paving the way for future discoveries in medicinal chemistry.