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Aliskiren

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Identification
Molecular formula
C30H53N3O6
CAS number
173334-57-1
IUPAC name
1-[6-amino-2-[(1-carboxy-3-phenyl-propyl)amino]hexanoyl]pyrrolidine-2-carboxylic acid
State
State

At room temperature, Aliskiren is typically found in a solid state.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
291.60
Boiling point (Kelvin)
564.75
General information
Molecular weight
609.83g/mol
Molar mass
609.8260g/mol
Density
1.2394g/cm3
Appearence

Aliskiren appears as a white to slightly yellowish crystalline powder.

Comment on solubility

Solubility of 1-[6-amino-2-[(1-carboxy-3-phenyl-propyl)amino]hexanoyl]pyrrolidine-2-carboxylic acid

The solubility of C30H53N3O6, also known as 1-[6-amino-2-[(1-carboxy-3-phenyl-propyl)amino]hexanoyl]pyrrolidine-2-carboxylic acid, can be quite intriguing due to its complex structure. Understanding the solubility of this compound involves various factors:

  • Polarity: The presence of multiple functional groups, such as carboxylic acids and amines, suggests that this compound may exhibit polar characteristics, potentially increasing its solubility in polar solvents like water.
  • Hydrogen Bonding: With the amino and carboxylic groups, the ability to form hydrogen bonds may enhance solubility, especially in aqueous environments.
  • Alkyl Chain Influence: The hydrophobic propyl group may hinder the complete solubility in water, possibly leading to a variable solubility profile depending on the solvent used.
  • Solvent Interaction: Solubility may significantly vary among different solvents. Solvents with similar polar features could dissolve the compound more effectively.

To summarize, while C30H53N3O6 is likely to display solubility in polar solvents due to its polar functional groups, the presence of hydrophobic regions complicates its overall solubility behavior. Understanding these interactions is crucial for applications in pharmaceuticals and material sciences.

Interesting facts

Interesting Facts about 1-[6-amino-2-[(1-carboxy-3-phenyl-propyl)amino]hexanoyl]pyrrolidine-2-carboxylic acid

This intriguing compound is a derivative of amino acids and presents a fascinating intersection of biochemistry and organic synthesis. As an amino acid analog, it encompasses a variety of functional groups that allow it to participate in numerous biological processes. Here are some noteworthy points about this unique compound:

  • Amino Acid Structure: The compound features a pyrrolidine ring, which is a five-membered cyclic amine that plays a significant role in protein structures and enzyme activity.
  • Potential Biological Activity: Given its structure, this compound could potentially exhibit activities similar to peptide hormones or neurotransmitters, making it a subject of interest in pharmacology and medicinal chemistry.
  • Modifications for Drug Design: The compound’s various functional groups make it a useful scaffold for the design and development of new pharmaceuticals, particularly in targeting specific biological pathways.
  • Research Interest: Scientists often study such complex compounds to understand their interactions at the molecular level, which can lead to discoveries in drug formulation and disease treatment.

The exploration of compounds like this enables researchers to delve deeper into the mechanisms of life at a molecular level, emphasizing the importance of chemical diversity in drug discovery and development.

As one researcher once said, “The magic of chemistry lies in its ability to create new compounds that can change the world.” This compound exemplifies that very magic.

Synonyms
N~2~-(1-carboxy-3-phenylpropyl)lysylproline
CHEMBL105890
SCHEMBL24062681
BBL009960
STK801362
AKOS005612998
AB04852
NCGC00094934-01
NCGC00094934-02
AS-56169
EN300-19836208
1-[6-Amino-2-(1-carboxy-3-phenyl-propylamino)-hexanoyl]-pyrrolidine-2-carboxylic acid
1-{6-amino-2-[(1-carboxy-3-phenylpropyl)amino]hexanoyl}pyrrolidine-2-carboxylic acid