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Solithromycin

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Identification
Molecular formula
C43H65N5O10F
CAS number
760981-83-7
IUPAC name
1-(5-cyano-2-pyridyl)-3-[2-(4-ethoxy-3-fluoro-2-pyridyl)ethyl]isothiourea
State
State

Solithromycin is typically found in a solid state at room temperature. It is stable under standard conditions and is usually handled as a finely divided powder in pharmaceutical applications.

Melting point (Celsius)
249.00
Melting point (Kelvin)
522.15
Boiling point (Celsius)
490.00
Boiling point (Kelvin)
763.15
General information
Molecular weight
503.55g/mol
Molar mass
503.5510g/mol
Density
1.4000g/cm3
Appearence

Solithromycin appears as a solid, characterized by a crystalline structure. The specific color and crystalline form can vary based on purity and formulation, but it is generally a white to off-white powder.

Comment on solubility

Solubility of 1-(5-cyano-2-pyridyl)-3-[2-(4-ethoxy-3-fluoro-2-pyridyl)ethyl]isothiourea

The compound 1-(5-cyano-2-pyridyl)-3-[2-(4-ethoxy-3-fluoro-2-pyridyl)ethyl]isothiourea (C43H65N5O10F) presents an intriguing case for solubility analysis due to its complex structure and varied functional groups.

When considering the solubility of this compound, several key factors come into play:

  • Polar and Non-polar Regions: The presence of the ethoxy and cyano groups suggests a balance of polar and non-polar character, which can enhance solubility in a variety of solvents.
  • Hydrogen Bonding: The isothiourea moiety may participate in hydrogen bonding, potentially increasing solubility in polar solvents such as water.
  • Fluorine Influence: The fluorine atom in the structure may impact overall polarity and solubility, generally enhancing solubility in fluorous solvents.

Though specific solubility data might not be easily accessible for this compound, based on its chemical structure, it is expected to exhibit:

  • Moderate solubility in polar solvents (e.g., water and ethanol)
  • Good solubility in organic solvents (e.g., chloroform and DMSO)

It’s important to note that solubility can be influenced by temperature, pH, and the presence of other solutes.

In summary, while exact solubility metrics are not provided, the chemical characteristics of 1-(5-cyano-2-pyridyl)-3-[2-(4-ethoxy-3-fluoro-2-pyridyl)ethyl]isothiourea indicate potential for versatile solubility in various environments, making it a compound of interest in research and applications.

Interesting facts

Interesting Facts about 1-(5-Cyano-2-pyridyl)-3-[2-(4-ethoxy-3-fluoro-2-pyridyl)ethyl]isothiourea

This intriguing compound belongs to a category of organic molecules known as isothioureas. Its unique structure and properties make it a subject of interest for both medicinal and agricultural chemistry.

Key Features

  • Diverse Applications: Isothioureas like this compound are often investigated for their potential in antitumor and antiviral therapies due to their ability to inhibit certain biological pathways.
  • Fluorine in Chemistry: The presence of fluorine in the ethoxy side chain can greatly influence the compound's reactivity and biological activity, making it a valuable element in drug design.
  • Pyridine Motifs: The compound contains pyridine rings, which are important in organic synthesis and have been found in numerous pharmaceuticals.

Moreover, this compound's complex structure poses compelling challenges for synthetic chemists. It demands precision in synthesis methods and purification processes. As chemists say, "Every complex molecule tells a story," and this is no exception. Exploring the synthetic pathways to create such a compound not only enhances our understanding of organic synthesis but also broadens our toolkit for creating new and effective drugs.

Future Implications

Given its structural attributes, 1-(5-cyano-2-pyridyl)-3-[2-(4-ethoxy-3-fluoro-2-pyridyl)ethyl]isothiourea may open new avenues in the development of targeted therapies and could serve as a lead compound in the quest for novel treatments. Researchers are encouraged to investigate further, as the interplay of the various functional groups might lead to significant breakthroughs in multiple fields.