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M223

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Identification
Molecular formula
C14H18N2O
CAS number
502174-91-8
IUPAC name
1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidin-2-one
State
State

The compound is typically found as a solid at room temperature.

Melting point (Celsius)
58.40
Melting point (Kelvin)
331.50
Boiling point (Celsius)
345.70
Boiling point (Kelvin)
618.80
General information
Molecular weight
246.30g/mol
Molar mass
248.3400g/mol
Density
1.1347g/cm3
Appearence

The compound appears as a white to off-white solid powder.

Comment on solubility

Solubility of 1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidin-2-one (C14H18N2O)

The solubility of 1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidin-2-one is an intriguing subject due to its unique molecular structure. Understanding the solubility behavior of this compound can provide valuable insights into its potential applications and interactions in various environments. Here are a few key points:

  • Solvent Dependence: The solubility of organic compounds like this one often varies significantly between different solvents. Polar solvents (e.g., water, ethanol) may show differing capacities compared to nonpolar solvents (e.g., hexane).
  • Factors Influencing Solubility: Several factors can impact the solubility of this compound:
    • Temperature: Increasing temperature typically enhances solubility for many organic compounds.
    • pH Levels: For compounds with functional groups that can ionize, the pH can considerably alter solubility.
    • Structural Aspects: The presence of functional groups such as the pyrrolidine ring may create hydrogen bonding opportunities, influencing solubility in polar solvents.
  • Practical Implications: The solubility behavior of this compound will be crucial in drug formulation and development, especially considering:
    • its pharmacokinetic properties.
    • the bioavailability of the compound when administered.

In conclusion, investigating the solubility of 1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidin-2-one allows for a deeper understanding of its physical chemistry, emphasizing the complex interplay between structure and solubility.

Interesting facts

Interesting Facts about 1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidin-2-one

This compound, with a complex structure, belongs to the class of pyrrolidines, which are notable for their diverse range of biological activities and therapeutic potentials. Here are some fascinating insights:

  • Structural Versatility: The presence of the pyrrolidinyl moieties in this compound gives it a unique structural profile that can facilitate interactions with biological targets, enhancing its efficacy.
  • Potential Applications: Compounds like 1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidin-2-one are often explored in medicinal chemistry for their potential as antidepressants or anxiolytics.
  • Research Interest: Researchers are increasingly interested in the functional modification of pyrrolidines to discover new pharmacological properties. The incorporation of but-2-ynyl offers intriguing possibilities for reactivity and activity.
  • Synthetic Challenges: The synthesis of such compounds can be quite challenging due to their multi-step synthesis pathways, requiring advanced techniques in organic synthesis.
  • Mechanism of Action: While specific mechanisms would require experimental validation, pyrrolidinyl structures are often associated with neurotransmitter modulation, which is key in developing mental health medications.

In summary, 1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidin-2-one showcases the rich potential that pyrrolidine derivatives offer in the field of organic and medicinal chemistry. Each new compound serves as a stepping stone towards groundbreaking discoveries and innovative treatments in the pharmaceutical landscape.

Synonyms
Oxotremorine
Oxytremorine
70-22-4
Oxotremorin
Tremorine, oxo-
2'-Oxopyrrolidino-1-pyrrolidino-4-butyne
1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidin-2-one
MLS000766260
5RY0UWH1JL
EINECS 200-728-0
NSC 330497
BRN 1530948
2-PYRROLIDINONE, 1-(4-(1-PYRROLIDINYL)-2-BUTYNYL)-
OXOTREMORINE [MI]
NSC-330497
CHEMBL7634
1-(4-(Pyrrolidin-1-yl)but-2-ynyl)pyrrolidin-2-one
2-Pyrrolidinone, 1-[4-(1-pyrrolidinyl)-2-butynyl]-
CHEBI:7851
DTXSID10220252
5-21-06-00370 (Beilstein Handbook Reference)
2-Pyrrolidinone,1-[4-(1-pyrrolidinyl)-2-butyn-1-yl]-
1-(2-OXOPYRROLIDINO)-4-PYRROLIDINO-2-BUTYNE
UNII-5RY0UWH1JL
Spectrum_001448
Spectrum_001875
Tocris-0843
Spectrum2_001568
Spectrum3_001599
Spectrum4_000912
Spectrum5_001099
Spectrum5_001686
Lopac-O-9126
oxotremorine-sesquifumarate
cid_4630
SCHEMBL2128
Lopac0_000914
BSPBio_003198
GTPL302
KBioGR_001404
KBioSS_001928
KBioSS_002398
DivK1c_000410
SPBio_001476
KBio1_000410
KBio2_001928
KBio2_002393
KBio2_004496
KBio2_004961
KBio2_007064
KBio2_007529
KBio3_002698
DTXCID10142743
NINDS_000410
HMS2089F17
HMS2231C13
HMS3372G17
BDBM50004665
NSC330497
WLN: T5NVTJ A2UU2- AT5NTJ
CCG-204996
SDCCGSBI-0050889.P003
IDI1_000410
NCGC00015773-01
NCGC00015773-02
NCGC00015773-03
NCGC00015773-04
NCGC00015773-05
NCGC00015773-10
NCGC00024821-01
NCGC00024821-02
NCGC00024821-03
SMR000528860
DB-055393
HY-170032
NS00037024
1-(4-pyrrolidino-2-butynyl)-2-pyrrolidinone
C07485
AB00053670-07
L001302
Q676896
SR-01000075154-3
1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
BRD-K21936341-051-02-4
BRD-K21936341-051-03-2
1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidinium
Oxotremorine1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
(oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one(Oxotremorine)
1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one (oxotremorphine)
200-728-0