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4'-Hydroxypropiophenone

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Identification
Molecular formula
C9H10O2
CAS number
70-70-2
IUPAC name
1-(4-hydroxyphenyl)propan-1-one
State
State

At room temperature, 4'-Hydroxypropiophenone is in a solid state. It is typically found in its crystalline form, which contributes to its stability and ease of handling for various laboratory procedures.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
150.17g/mol
Molar mass
150.1740g/mol
Density
1.1254g/cm3
Appearence

4'-Hydroxypropiophenone typically appears as a white to off-white crystalline solid. It is a relatively stable compound and is often used in organic synthesis and as a starting material for various chemical reactions. Its crystalline nature makes it easy to handle in the lab environment.

Comment on solubility

Solubility of 1-(4-hydroxyphenyl)propan-1-one (C9H10O2)

1-(4-hydroxyphenyl)propan-1-one, also known as hydroxyacetophenone, exhibits interesting solubility characteristics due to its unique molecular structure. Understanding its solubility can help in various applications, such as pharmaceuticals and organic synthesis.

General Solubility

This compound is generally considered to be:

  • Soluble in organic solvents such as ethanol and acetone.
  • Practically insoluble in water due to the non-polar hydrocarbon part of the molecule.

Factors Influencing Solubility

The solubility characteristics can largely be attributed to:

  1. The presence of the hydroxyl group (–OH), which can engage in hydrogen bonding.
  2. Van der Waals forces from the alkyl chain and the aromatic ring.
  3. The overall molecular polarity resulting from the functional groups in the structure.

In summary, while 1-(4-hydroxyphenyl)propan-1-one shows effective solubility in organic solvents, it is less compatible with polar solvents like water. This characteristic should be carefully considered when utilizing this compound in chemical processes or applications.

Interesting facts

Interesting Facts About 1-(4-hydroxyphenyl)propan-1-one

1-(4-hydroxyphenyl)propan-1-one, also known as p-hydroxyacetophenone, is a fascinating compound that showcases the interplay between structure and function in organic chemistry. This compound belongs to the class of aromatic ketones and has several significant applications and properties:

  • Antioxidant Properties: Research has demonstrated that p-hydroxyacetophenone exhibits antioxidant capabilities, making it a valuable compound in the development of pharmaceuticals aimed at reducing oxidative stress in cells.
  • Flame Retardant: Its chemical structure lends itself to applications as a flame retardant, highlighting the importance of ketones in material safety.
  • Use in Synthesis: This compound plays a crucial role in synthesizing various organic compounds, serving as a precursor in the production of more complex molecules.
  • Historical Significance: The study of this compound has contributed significantly to the understanding of aromatic substitution reactions, a core concept in organic chemistry curricula.

Furthermore, it's fascinating to note how the placement of the hydroxyl group at the para position affects not only the physical properties of the compound but also its reactivity and interaction with biological systems. As a chemistry student or scientist, studying p-hydroxyacetophenone can offer insights into:

  • Structure-Activity Relationships: Understanding how small changes in molecular structure can drastically alter a compound’s function and utility.
  • Interdisciplinary Applications: The compound’s properties bridge the fields of chemistry, materials science, and pharmacology, showcasing the relevance of chemistry in various sectors.

In conclusion, 1-(4-hydroxyphenyl)propan-1-one is more than just a chemical formula; it represents a compound with multifaceted significance in both research and practical applications. As scientists continue to explore its potential, this compound is certain to maintain its relevance in the scientific community.

Synonyms
4'-Hydroxypropiophenone
70-70-2
Paroxypropione
4-Hydroxypropiophenone
1-(4-hydroxyphenyl)propan-1-one
p-Hydroxypropiophenone
Mepal
Paroxypropion
Frenantol
Frenohypon
Profenone
Proxiphenon
Paroxon
p-Propiophenol
p-Propionylphenol
1-Propanone, 1-(4-hydroxyphenyl)-
Hypophenon
Possipione
Sterofenon
Frenormon
Hypostat
Ibiopopp
Frenon
Bio-fren
4-Propionylphenol
p-Oxypropiophenone
Paraoxypropiophenone
Paroxipropiona
1-(4-Hydroxyphenyl)-1-propanone
Usaf ek-3302
Parossipropione
Paroxypropionum
Possipion
p-Hydroxyphenyl-1-propanone
Ethyl p-hydroxyphenyl ketone
Parossipropione [DCIT]
B-360
H 365
H-365
1-(p-Hydroxyphenyl)-1-propanone
Paroxypropione [INN:DCF]
Propiophenone, 4'-hydroxy-
Paroxypropionum [INN-Latin]
Paroxipropiona [INN-Spanish]
1-(4-Hydroxy-phenyl)-propan-1-one
4-Propanoylphenol
NSC 2834
NSC-2834
B 360
EINECS 200-743-2
BRN 0907511
4-Hydroxypropiophenon
P.O.P.
DTXSID8023426
Paroxypropione (INN)
UNII-X9952001TG
AI3-03719
MFCD00002361
PAROXYPROPIONE [MI]
X9952001TG
PAROXYPROPIONE [INN]
p-Hydroxypropiophenone (JAN)
MLS000069406
PAROXYPROPIONE [MART.]
CHEMBL312311
DTXCID103426
PAROXYPROPIONE [WHO-DD]
CHEBI:32352
NSC2834
4-08-00-00441 (Beilstein Handbook Reference)
P-HYDROXYPROPIOPHENONE [JAN]
NCGC00018097-04
NCGC00018097-06
SMR000059092
WLN: QR DV2
Paroxypropionum (INN-Latin)
Paroxipropiona (INN-Spanish)
PAROXYPROPIONE (MART.)
CAS-70-70-2
para-Hydroxypropiophenone
p-Hydroxypropiophenon
VANATONE
4-hydroxy propiophenone
4`-Hydroxypropiophenone
4'-hydroxy-propiophenone
4''-Hydroxypropiophenone
Opera_ID_1001
Ethyl 4-Hydroxyphenyl Ketone
SCHEMBL440470
4?-HYDROXYPROPIOPHENONE
4'-Hydroxypropiophenone, 98%
F1995-0235
HMS2235G15
HMS3264A14
HMS3372E08
Pharmakon1600-01506169
1-(4-hydroxyphenyl)-propan-1-one
BCP26379
HY-B1353
NSC33949
Tox21_110822
AC7855
BBL011845
BDBM50177402
NSC-33949
NSC760386
s5396
STK397478
AKOS000120374
Tox21_110822_1
CCG-214030
CS-7973
FH71324
NSC-760386
NCGC00018097-01
NCGC00018097-02
NCGC00018097-03
NCGC00018097-05
NCGC00022475-03
NCGC00022475-04
AC-10985
AS-12055
DA-59760
SY003666
H0299
NS00003309
EN300-21481
D01870
SBI-0653508.0001
4 inverted exclamation mark -Hydroxypropiophenone
4 inverted exclamation marka-Hydroxypropiophenone
AB00384258_14
AF-676/00077028
SR-01000002967
SR-01000002967-2
BRD-K07441213-001-14-8
BRD-K07441213-001-18-9
Q19598411
Z104499156
200-743-2