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Thymidine

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Identification
Molecular formula
C10H14N2O5
CAS number
50-89-5
IUPAC name
1-[4-hydroxy-5-(hydroxymethyl)-2,3,3,4,5-pentamethyl-tetrahydrofuran-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione
State
State

Thymidine is typically found in a solid state at room temperature. It is stable under normal conditions, making it suitable for various biochemical applications.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.15
Boiling point (Celsius)
269.80
Boiling point (Kelvin)
542.95
General information
Molecular weight
242.23g/mol
Molar mass
242.2290g/mol
Density
1.6700g/cm3
Appearence

Thymidine appears as white crystalline powder. It has a characteristic crystalline structure and appears as a fine, white substance in its pure form. Its crystalline nature contributes to its consistent appearance, often utilized in laboratory settings.

Comment on solubility

Solubility of 1-[4-hydroxy-5-(hydroxymethyl)-2,3,3,4,5-pentamethyl-tetrahydrofuran-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione

The solubility of the compound with the formula C10H14N2O5 can be influenced by several factors, primarily due to its complex structure and the presence of multiple functional groups. This compound features hydroxyl groups, which typically enhance solubility in polar solvents due to hydrogen bonding.

Factors Affecting Solubility

  • Polarity: The high degree of hydroxyl substitution suggests it could be significantly soluble in polar solvents like water.
  • Hydrogen Bonding: Functional groups such as hydroxymethyl and hydroxy can form strong hydrogen bonds, potentially increasing solubility.
  • Molecular Weight: The moderate molecular weight may also facilitate dissolution in various solvents.

Quote: "In chemistry, the saying 'like dissolves like' often applies. Thus, the presence of polar groups usually leads to better solubility in polar environments."

Overall, while specific solubility data for this compound may not be readily available, one can anticipate a reasonable solubility in water and other polar solvents due to the presence of multiple hydroxyl groups. However, the full extent of its solubility would require experimental determination to confirm its behavior in various conditions.

Interesting facts

Interesting Facts about 1-[4-hydroxy-5-(hydroxymethyl)-2,3,3,4,5-pentamethyl-tetrahydrofuran-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione

This unique compound, often referred to for its complex structure and notable functional groups, is a fascinating subject of study in both organic and medicinal chemistry. Here are some intriguing aspects worth noting:

  • Structural Complexity: The compound contains both a tetrahydrofuran ring and a pyrimidine-2,4-dione moiety, making it a valuable target for synthetic chemists. Its structure exhibits a harmonious integration of various functional groups, which can potentially offer diverse interactions.
  • Biological Relevance: Pyrimidine derivatives are well-known for their roles in biological systems, particularly in nucleic acid structures (DNA/RNA). Compounds similar to this one have been studied for their potential as antiviral and anticancer agents, showcasing important therapeutic implications.
  • Hydroxymethyl Groups: The presence of multiple hydroxymethyl groups indicates that this compound can undergo further chemical transformations, making it a versatile intermediate in organic synthesis. Hydroxymethyl groups are known to increase aqueous solubility and enhance the compound's reactivity.
  • Synthetic Applications: Due to its complex and multifunctional structure, this compound could serve as a building block for synthesizing more complex molecules, paving the way for novel functional materials in polymer chemistry.

In summary, 1-[4-hydroxy-5-(hydroxymethyl)-2,3,3,4,5-pentamethyl-tetrahydrofuran-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione is a remarkable compound that not only holds importance in theoretical studies but also shows potential for practical applications in pharmaceutical and organic synthesis domains. Its complexity and versatility make it a compound worthy of further exploration.