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4'-Fluoropropiophenone

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Identification
Molecular formula
C19H20FNO2
CAS number
771-93-7
IUPAC name
1-(4-fluorophenyl)-4-[4-hydroxy-4-(p-tolyl)-1-piperidyl]butan-1-one
State
State

At room temperature, this compound is in a solid state. It is stable under standard conditions but should be stored in a cool, dry place to maintain its stability and prevent any possible degradation.

Melting point (Celsius)
54.00
Melting point (Kelvin)
327.15
Boiling point (Celsius)
284.00
Boiling point (Kelvin)
557.15
General information
Molecular weight
267.33g/mol
Molar mass
267.3340g/mol
Density
1.1460g/cm3
Appearence

The compound is typically a crystalline solid at room temperature. It can appear as a white to off-white powder or crystalline material. Its physical appearance may vary based on purity and form, such as powder or larger crystalline blocks.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-[4-hydroxy-4-(p-tolyl)-1-piperidyl]butan-1-one

The compound 1-(4-fluorophenyl)-4-[4-hydroxy-4-(p-tolyl)-1-piperidyl]butan-1-one, with the chemical formula C19H20FNO2, showcases specific solubility characteristics that are crucial for its application and bioavailability.

Key Aspects of Solubility

  • Polarity: The presence of functional groups such as the hydroxyl group (-OH) contributes to enhanced solubility in polar solvents like water.
  • Hydrophobic Segments: The aromatic rings and butanone structure may lead to increased solubility in organic solvents, including ethanol and dimethyl sulfoxide (DMSO).
  • Influence of Temperature: Solubility typically increases with temperature; hence, warming the solvent can enhance dissolution.
  • pH Sensitivity: The solubility may also vary with pH levels, as the ionization of the hydroxyl group can affect its overall solubility profile.

Overall, the physicochemical properties of this compound imply that it has a balanced solubility profile that allows for diverse applications. For practical purposes, it is advisable to conduct empirical solubility tests in various solvents to assess its behavior comprehensively. Understanding solubility is essential for predicting the compound's performance in biological systems and industrial applications.

Interesting facts

Interesting Facts about 1-(4-fluorophenyl)-4-[4-hydroxy-4-(p-tolyl)-1-piperidyl]butan-1-one

This compound, known for its complex structure, belongs to a class of molecules that often exhibit significant biological activity. Here are some intriguing aspects:

  • Pharmacological Relevance: This compound may play a role in the field of pharmaceuticals, particularly in the development of medications targeting neurological disorders. Its structural features suggest potential interaction with neurotransmitter systems.
  • Structural Complexity: The presence of both a fluorophenyl group and a piperidinyl moiety contribute to the compound's unique properties. The fluorine atom enhances lipophilicity, which can improve the compound's ability to cross biological membranes.
  • Hydroxyl Group Impact: The hydroxyl group in the structure can significantly alter the compound’s solubility and reactivity, possibly influencing its biological activity and pharmacokinetics.
  • Analytical Techniques: The study of this compound often involves sophisticated analytical methods, such as NMR and mass spectrometry, which help in elucidating its structure and confirming purity.
  • Research Potential: Given its structural characteristics, this compound offers exciting opportunities for researchers exploring new therapeutic avenues. Its diverse functional groups are ideal for synthetic modifications, leading to variations that could enhance efficacy or reduce side effects.

In the words of a renowned chemist, "The beauty of synthetic chemistry lies not only in the ability to create new compounds but also in understanding the vast potential they hold for innovative solutions." This compound is a quintessential example of how molecular design can pave the way for therapeutic advancements.


Overall, the scientific community continues to explore compounds like this one, paving the way for future discoveries that may have profound impacts on health and medicine.

Synonyms
Moperone
1050-79-9
Methylperidol
Meperon
Moperona
Moperone [INN]
Luvatrena
Moperonum
Mopiperone
Moperonum [INN-Latin]
Moperona [INN-Spanish]
Moperone (INN)
R 1658
1-(4-fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]butan-1-one
UNII-OU730881W5
MOPERONE [MI]
EINECS 213-887-6
MOPERONE [WHO-DD]
moperone hydrochloride
OU730881W5
4'-Fluoro-4-(4-hydroxy-4-p-tolylpiperidino)butyrophenone
DTXSID6049062
Butyrophenone, 4'-fluoro-4-(4-hydroxy-4-p-tolylpiperidino)-
1-Butanone, 1-(4-fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)-1-piperidinyl]-
p-Fluoro-4-(4'-hydroxy-4'-p-tolylpiperidino)butyrophenone
omega-(4-Hydroxy-4-p-tolylpiperidino)-p-fluorobutyrophenone
Moperonum (INN-Latin)
Moperona (INN-Spanish)
p-Fluoro-4-(4'-hydroxy-4'-p-methylphenylpiperidino)butyrophenone
1-Butanone, 1-(4-fluorophenyl)-4-(4-hydroxy-4-(4-methylphenyl)-1-piperidinyl)-
Moperone hydrochloride [JAN]
DTXCID7028988
4'-Fluoro-4-(4-hydroxy-4-p-tolylpiperidino)butyrophenone;4'-Fluoro-4-(4-hydroxy-4-p-tolylpiperidino)butyrophenone
NCGC00188430-01
1-(4-fluorophenyl)-4-(4-hydroxy-4-(4-methylphenyl)piperidin-1-yl)butan-1-one
4'-fluoro-4-(4-hydroxy-4-4-tolylpiperidino)butyrophenone
1-(4-Fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)-1-piperidinyl]-1-butanone
SCHEMBL34340
CHEMBL2104700
BDBM81486
N05AD04
CHEBI:135500
NSC_4249
AKOS030254497
DB13554
FM26075
HY-W777345
CAS_1050-79-9
NS00005971
D02623
SBI-0654122.0001
L000665
Q6908807
gamma-(4-hydroxy-4-p-methylphenylpiperidino)-p-fluorobutyrophenone
1-(4-Fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)-1-piperidinyl]-1-butanone #
213-887-6