Interesting facts
Interesting Facts about 1-(4-chlorophenyl)-N-methyl-propan-2-amine
1-(4-chlorophenyl)-N-methyl-propan-2-amine, commonly known in the scientific community with names like 4-chloroamphetamine, is an intriguing compound in the field of chemistry due to its unique structure and potential applications. Here are some fascinating aspects of this compound:
- Structure and Functional Groups: This compound features a 4-chlorophenyl ring, which is a chlorinated derivative of phenyl, contributing to its distinct properties. The presence of the amino group enhances its reactivity, making it an interesting subject for studies in organic synthesis.
- Pharmacological Interest: 4-chloroamphetamine is studied for its action as a psychostimulant, possessing structural similarities to other compounds that affect neurotransmitter systems, particularly serotonin and dopamine. This makes it a point of interest for research in neurochemistry and pharmacology.
- Historical Context: Compounds like 4-chloroamphetamine have roots in the exploration of stimulant drugs and have influenced the development of medicinal chemistry, showcasing how small modifications to a chemical structure can yield significant changes in biological activity.
- Synthesis and Preparation: Its synthesis typically involves the reaction of commercially available precursors, with a focus on controlling the reaction conditions to obtain the desired purity and yield. This process can provide insights into reaction mechanisms and optimization in organic chemistry.
Overall, 1-(4-chlorophenyl)-N-methyl-propan-2-amine serves as a prime example of how a single compound can bridge various fields of study, ranging from organic chemistry to pharmacology. As researchers strive to understand its properties and effects, this compound continues to be an important subject of investigation in chemical science.
Synonyms
p-Chloro-N-methylamphetamine
Chlormethamphetamine
pCMA
1199-85-5
S-33
1-(4-chlorophenyl)-N-methylpropan-2-amine
Ro 4-6861
p-chloromethamphetamine
4-Chloromethamphetamine
d-1-para-Chloro-methylamphetamine
540OPI9I4Z
p-Chloro-N,alpha-dimethylphenethylamine
BRN 2088422
UNII-540OPI9I4Z
d-1-para-Chloro-methylamphetamine [French]
[1-(4-chlorophenyl)propan-2-yl](methyl)amine
Chloromethamphetamine
p-Aminomethamphetamine
p-Chlormethamphetamine
Chloromethylamphetamine
Parachloromethamphetamine
4-Chloro-N,alpha-dimethylbenzeneethanamine
Phenethylamine, p-chloro-N,alpha-dimethyl-
Phenethylamine, p-chloro-N,.alpha.-dimethyl-
4-CMA
Benzeneethanamine, 4-chloro-N,.alpha.-dimethyl-
4-12-00-02618 (Beilstein Handbook Reference)
SCHEMBL178533
P-CHLOROMETHYLAMPHETAMINE
PARA-CHLOROMETHAMPHETAMINE
DTXSID00897230
XXLWNLKEOWWHDC-UHFFFAOYSA-N
BAA19985
p-Chloro-N,.alpha.-dimethylphenethylamine
PD046022
RO-4-6861
NS00017733
1-(4-Chlorophenyl)-N-methyl-2-propanamine #
Q21098971
Solubility of 1-(4-chlorophenyl)-N-methyl-propan-2-amine (C10H14ClN)
The solubility of 1-(4-chlorophenyl)-N-methyl-propan-2-amine in various solvents plays a crucial role in its applications across chemistry and pharmacology. This compound is generally characterized by moderate solubility in polar organic solvents such as:
However, it exhibits lower solubility in non-polar solvents, which is typical for compounds containing both aromatic and aliphatic structures. Understanding the solubility behavior can be summarized as follows:
As a rule of thumb, it can be said that the structural characteristics of the compound significantly influence its solubility preferences. Observing the interactions between solute and solvent is essential for proper usage in synthesis and formulation. Hence, researchers often perform solubility tests to predict behavior in various solutions, providing invaluable insights into the compound's usability in different chemical contexts.