1-(4-butoxyphenyl)sulfonyl-4-(methanesulfonamido)pyrrolidine-2-carbohydroxamic acid

Identification

Molecular formula

C₁₆H₂₄N₂O₇S₂

CAS number

885499-61-6

IUPAC name

1-(4-butoxyphenyl)sulfonyl-4-(methanesulfonamido)pyrrolidine-2-carbohydroxamic acid

State

At room temperature, this compound is likely in a solid state.

Melting point (Celsius)

205.00

Melting point (Kelvin)

478.15

Boiling point (Celsius)

570.00

Boiling point (Kelvin)

843.15

General information

Molecular weight

448.56g/mol

Molar mass

448.5580g/mol

Density

1.3500g/cm³

Appearence

This compound is expected to be a white to off-white crystalline powder.

Comment on solubility

Solubility Characteristics of 1-(4-butoxyphenyl)sulfonyl-4-(methanesulfonamido)pyrrolidine-2-carbohydroxamic acid

The solubility of 1-(4-butoxyphenyl)sulfonyl-4-(methanesulfonamido)pyrrolidine-2-carbohydroxamic acid, with the molecular formula C₁₆H₂₄N₂O₇S₂, is influenced by various factors due to its complex structure. The presence of multiple polar functional groups suggests that this compound may have variable solubility in different solvents.

Factors Affecting Solubility

Polarity: The molecule contains polar sulfonamide and hydroxamic acid groups, which may enhance solubility in polar solvents such as water.
Hydrophobic Interactions: The butoxyphenyl group may introduce hydrophobic characteristics, potentially decreasing solubility in water but increasing it in organic solvents like ethanol or acetone.
Temperature: Like many compounds, solubility may increase with temperature, allowing for better dissolution in higher temperature solvents.

Generally, we can anticipate that:

In water: The compound may exhibit moderate solubility due to its size and functional groups.
In organic solvents: Solubility may be higher, particularly in non-polar or slightly polar solvents.

In conclusion, while specific solubility data may vary, the unique structure of this compound likely contributes to its diverse solubility profile across different solvents. Understanding these characteristics is crucial for applications in various chemical contexts.

Interesting facts

Exploring 1-(4-butoxyphenyl)sulfonyl-4-(methanesulfonamido)pyrrolidine-2-carbohydroxamic Acid

This fascinating compound is a member of the wide array of sulfonamide derivatives, which are known for their diverse applications in medicinal chemistry. Here are some interesting facts and insights into the structure and potential of this compound:

Medical Relevance: Compounds of this nature often display pharmacological activities, which make them valuable candidates in drug development. The incorporation of sulfonamides has been linked to antibacterial properties.
Structural Complexity: The presence of both a pyrrolidine ring and multiple functional groups, including hydroxy and sulfonamide moieties, contributes to the compound's potential to interact with biological systems in unique ways.
Design Versatility: The butoxyphenyl and methanesulfonamido groups allow for fine-tuning of the compound's physicochemical properties, potentially influencing solubility, permeability, and binding affinity to target proteins.
Hydroxamic Acid Feature: The hydroxamic acid group is often found in inhibitors of metalloenzymes, which are important therapeutic targets in cancer treatment. This highlights the compound's potential in various medicinal applications.
Research Potential: As researchers continue to investigate the structure-activity relationship (SAR) of sulfonamide derivatives, this compound may provide insights that lead to new therapeutic strategies.

In summary, 1-(4-butoxyphenyl)sulfonyl-4-(methanesulfonamido)pyrrolidine-2-carbohydroxamic acid is not just a complex chemical; it embodies the fusion of structural diversity and pharmacological potential, making it a subject of interest in modern chemistry and drug discovery.

Synonyms

PD042859