Interesting facts
Interesting Facts about 1-(4-acetylphenyl)sulfonyl-3-cyclohexyl-urea
1-(4-acetylphenyl)sulfonyl-3-cyclohexyl-urea is a compound that blends the worlds of organic chemistry and medicinal applications. Its unique structure includes a sulfonylurea functional group, which is often utilized in the pharmaceutical industry for designing drugs. Here are some engaging facts about this intriguing compound:
- Medicinal Potential: The sulfonylurea group is well-known for its role in treating type 2 diabetes. By stimulating insulin secretion from the pancreas, compounds like this one can help regulate blood glucose levels.
- Cyclohexyl Moiety: The cyclohexyl part of the compound can enhance lipophilicity, potentially improving the bioavailability of the compound when used in drug formulations.
- Versatile Drug Design: This compound exemplifies how modifying the phenyl ring, such as adding an acetyl group, can fine-tune the biological activity and specificity of the resulting drug interactions.
- Green Chemistry: The synthesis of sulfonylureas like this compound often involves approaches that prioritize environmental sustainability, reducing waste and enhancing efficiency in chemical reactions.
In a laboratory setting, studying the properties of such compounds can lead to breakthroughs in understanding drug interactions and biological mechanisms. As a scientist or chemistry student, one is continually reminded of how a seemingly simple change in structure can result in significant differences in function and effectiveness:
"The key to innovation in drug design lies in a deep understanding of molecular interactions and structural nuances."
Overall, 1-(4-acetylphenyl)sulfonyl-3-cyclohexyl-urea serves as a fascinating example of how chemistry can be applied to real-world health challenges.
Synonyms
acetohexamide
968-81-0
Dymelor
Acetohexamid
Dimelor
Gamadiabet
Hypoglicil
Metaglucina
Tsiklamid
Minoral
Ordimel
Acetohexamida
Acetohexamidum
1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea
N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea
1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea
CCRIS 4
NCI-C03247
Acetohexamidum [INN-Latin]
Acetohexamida [INN-Spanish]
1-(p-Acetylbenzenesulfonyl)-3-cyclohexylurea
HSDB 3280
U-14812
UNII-QGC8W08I6I
EINECS 213-530-4
QGC8W08I6I
4-Acetyl-N-((cyclohexylamino)carbonyl)benzenesulfonamide
4-Acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide
NSC-759128
BRN 2225115
U 14812
DTXSID7020007
CHEBI:28052
N-(p-Acetylbenzenesulfonyl)-N'-cyclohexylurea
Benzenesulfonamide, 4-acetyl-N-[(cyclohexylamino)carbonyl]-
DTXCID707
Benzenesulfonamide, 4-acetyl-N-((cyclohexylamino)carbonyl)-
3-(4-acetylbenzenesulfonyl)-1-cyclohexylurea
Acetohexamide-d11
4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide
Urea, 1-((p-acetylphenyl)sulfonyl)-3-cyclohexyl-
MFCD00072156
NSC 759128
Acetohexamide [USAN)
NCGC00015014-05
Acetohexamide [USAN:USP:INN:BAN:JAN]
CAS-968-81-0
1-(4-acetylphenyl)sulfonyl-3-cyclohexyl-urea
1-[(p-Acetylphenyl)sulfonyl]-3-cyclohexylurea
Acetohexamidum (INN-Latin)
ACETOHEXAMIDE [USAN]
Acetohexamida (INN-Spanish)
Urea, 1-[(p-acetylphenyl)sulfonyl]-3-cyclohexyl-
ACETOHEXAMIDE (MART.)
ACETOHEXAMIDE [MART.]
4-acetyl-N-(cyclohexylcarbamoyl)benzene-1-sulfonamide
dimelin (antidiabetic)
BENZENESULFONAMIDE, 4-ACETYL-N-((CYCLOHEXYLAMINO)CARBONYL)
ACETOHEXAMIDE (USP IMPURITY)
ACETOHEXAMIDE [USP IMPURITY]
Acetohexamide (USAN:USP:INN:BAN:JAN)
Dymelor (TN)
SR-01000075539
acetoesamide
3-cyclohexyl-1-(p-acetylphenylsulfonyl)urea
Prestwick_3
1-((4-acetylbenzene)sulfonyl)-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide
1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide
2468796-77-0
GAMADIABER
4-Acetyl-N-[(cyclohexylamino)-carbonyl]benzenesulfonamide
Lopac-A-178
Acetohexamide (Standard)
Prestwick0_000055
Prestwick1_000055
Prestwick2_000055
Prestwick3_000055
A-178
1-(4-acetylbenzenesulfonyl)-3-cyclohexylurea
ACETOHEXAMIDE [MI]
ACETOHEXAMIDE [INN]
ACETOHEXAMIDE [JAN]
ACETOHEXAMIDE [HSDB]
CHEMBL1589
Lopac0_000088
SCHEMBL37620
ACETOHEXAMIDE [VANDF]
BSPBio_000209
MLS002154186
SPBio_002130
ACETOHEXAMIDE [WHO-DD]
BPBio1_000231
GTPL6793
HY-B0881R
A10BB31
Acetohexamide (JP17/USP/INN)
Acetohexamide, analytical standard
HMS1568K11
HMS2093H21
HMS2095K11
HMS2236M07
HMS3260A18
HMS3372B02
HMS3712K11
Pharmakon1600-01505425
ACETOHEXAMIDE [ORANGE BOOK]
BCP34666
HY-B0881
Tox21_110067
Tox21_202022
Tox21_302735
Tox21_500088
GS4036
NSC759128
s5717
AKOS015916290
Tox21_110067_1
CCG-204183
DB00414
FA16951
LP00088
SDCCGSBI-0050076.P003
NCGC00015014-01
NCGC00015014-02
NCGC00015014-03
NCGC00015014-04
NCGC00015014-06
NCGC00015014-07
NCGC00015014-08
NCGC00015014-11
NCGC00015014-15
NCGC00016555-01
NCGC00091230-01
NCGC00091230-02
NCGC00091230-03
NCGC00091230-04
NCGC00256467-01
NCGC00259571-01
NCGC00260773-01
MS-24845
SMR001233477
SBI-0050076.P002
DB-057652
EU-0100088
NS00006055
C06806
D00219
EN300-123648
F85186
1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea
A845651
Dymelor; Gamadiabet; Acetohexamid; Dimelin; Dimelor
Q4673274
SR-01000075539-1
SR-01000075539-3
SR-01000075539-6
BRD-K52960356-001-03-1
BRD-K52960356-001-06-4
BRD-K52960356-001-13-0
BRD-K52960356-001-15-5
N-(4-ACETYLBENZENESULFONYL)-N'-CYCLOHEXYLUREA
Z1552195936
1-Acetyl-4-(([(cyclohexylamino)carbonyl]amino)sulfonyl)benzene #
4-Acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide;Acetohexamid;Dimelin
213-530-4
TF9
Solubility of 1-(4-acetylphenyl)sulfonyl-3-cyclohexyl-urea
The solubility of 1-(4-acetylphenyl)sulfonyl-3-cyclohexyl-urea, with the chemical formula C14H16N2O4S, can be influenced by various factors. Understanding the solubility characteristics is crucial for its application in chemical processes and formulations. Here are some key points to consider:
In general, this compound is expected to have moderate solubility properties, making it versatile for various applications where a balance between aqueous and organic solubility is needed. As a rule of thumb, "like dissolves like," and depending on the specific use case, it is crucial to identify the optimal solvent for desired results.