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Almorexant

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Identification
Molecular formula
C32H40N4O
CAS number
872728-81-9
IUPAC name
1-[4-[5-[4-[amino-(cyclobutylamino)methyl]phenyl]-2-furyl]phenyl]-N'-cyclobutyl-methanediamine
State
State

In its pure form, Almorexant is a solid at room temperature.

Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
518.85
Boiling point (Kelvin)
792.00
General information
Molecular weight
556.68g/mol
Molar mass
556.6820g/mol
Density
1.1800g/cm3
Appearence

Almorexant appears as a solid crystalline substance. The color can vary from white to off-white.

Comment on solubility

Solubility of 1-[4-[5-[4-[amino-(cyclobutylamino)methyl]phenyl]-2-furyl]phenyl]-N'-cyclobutyl-methanediamine

The compound 1-[4-[5-[4-[amino-(cyclobutylamino)methyl]phenyl]-2-furyl]phenyl]-N'-cyclobutyl-methanediamine (C32H40N4O) presents intriguing solubility characteristics due to its complex structure. Here are some key points to consider:

  • Polar and Nonpolar Characteristics: The molecule contains both polar (amine and furan groups) and nonpolar (cyclobutyl and phenyl groups) regions. This dual nature can influence its solubility profile in various solvents.
  • Solvent Interaction: It is likely to exhibit greater solubility in polar solvents such as methanol or water, as the presence of amino groups can lead to hydrogen bonding.
  • Solubility in Organic Solvents: Conversely, less polar organic solvents like chloroform or toluene may also dissolve the compound due to its hydrophobic areas, although to a lesser extent.
  • Temperature Effects: As with many organic compounds, the solubility can vary significantly with temperature—often increasing with temperature due to enhanced molecular motion.

In conclusion, while the precise solubility of C32H40N4O will depend on the specific conditions employed, understanding the balance of its polar and nonpolar features is essential for predicting its behavior in different solvents. As the saying goes, "like dissolves like," and in this case, recognizing the distinct functionalities of the compound can guide us to the most appropriate solvents for dissolution.

Interesting facts

Interesting Facts about 1-[4-[5-[4-[amino-(cyclobutylamino)methyl]phenyl]-2-furyl]phenyl]-N'-cyclobutyl-methanediamine

This compound is a fascinating example of organic chemistry, showcasing the intricate relationships between structure and function. Here are some intriguing insights:

  • Complex Structure: The compound features multiple functional groups and cyclic structures, notably the cyclobutyl moiety and various phenyl rings. This complexity can lead to unique properties and interactions.
  • Potential Applications: Due to its sophisticated structure, compounds like this one are often explored for use in pharmaceuticals. The incorporation of amine groups can enhance biological activity and interaction with biological targets.
  • Structure Activity Relationship (SAR): The presence of the amino group and the furyl moiety can significantly affect the compound's reactivity and binding affinity to biological receptors. Understanding its SAR can lead to the design of more effective drugs.
  • Intriguing Chemistry: The cyclobutyl group not only contributes to the compound's three-dimensional shape but also can influence its stability and reactivity. This makes such compounds interesting in the fields of medicinal and synthetic chemistry.
  • Research Implications: Compounds with multiple functional and cyclic groups like this are often the subject of study for their potential in treating various diseases. Their complex nature invites ongoing research into how these compounds interact in biological systems.

In summary, 1-[4-[5-[4-[amino-(cyclobutylamino)methyl]phenyl]-2-furyl]phenyl]-N'-cyclobutyl-methanediamine is not just another compound; it is a gateway into a multitude of scientific explorations that blend organic chemistry, pharmacology, and materials science. As researchers delve deeper, who knows what new applications may emerge?

Synonyms
(S,R)-(furan-2,5-diyldibenzene-4,1-diyl)bis(N-cyclobutylmethanediamine)