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L-ephedrine

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Identification
Molecular formula
C10H15NO2
CAS number
299-42-3
IUPAC name
1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone
State
State

At room temperature, L-ephedrine is typically in a solid state in the form of a crystalline powder.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.15
Boiling point (Celsius)
218.00
Boiling point (Kelvin)
491.15
General information
Molecular weight
183.25g/mol
Molar mass
183.2510g/mol
Density
1.1410g/cm3
Appearence

The pure compound is typically a white or off-white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone

The solubility of 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone can be characterized by several factors that influence its behavior in different environments. This compound exhibits both hydrophilic and lipophilic characteristics:

  • Hydroxyl Groups: The presence of two –OH (hydroxyl) groups on the aromatic ring increases the compound's affinity for polar solvents, particularly water. This can lead to moderate solubility in aqueous solutions.
  • Isopropylamino Group: The isopropylamino part adds a bulky, hydrophobic element that may reduce overall solubility in water but can enhance solubility in organic solvents.
  • pH Influence: The solubility may vary significantly with pH, as ionization of the amino group can occur at different pH levels, potentially increasing solubility in basic conditions due to ionization.
  • Temperature Effects: In general, an increase in temperature can improve solubility; hence, warmer solvents could potentially dissolve more of this compound.

In conclusion, while 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone shows some level of solubility in polar solvents, its overall solubility is a delicate balance of its structural features. As researchers explore its applications, understanding these solubility characteristics is crucial:

"Solubility is not merely a function of structure, but also of the environment."

Therefore, solubility studies under varying conditions will provide deeper insights into its practical uses.

Interesting facts

Interesting Facts About 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone

1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone is a fascinating compound with notable properties and potential applications in various fields. Here are some remarkable aspects:

  • Biochemical Significance: This compound is structurally related to catecholamines, which play crucial roles in neurotransmission and hormonal regulation within the body, making it of particular interest in neurochemistry.
  • Research Applications: Due to its catechol structural motif, it is often studied for its potential role in the development of drugs targeting neurodegenerative disorders as well as mood disorders.
  • Antioxidant Activity: The presence of hydroxyl groups in the compound is known to enhance antioxidant properties, suggesting potential uses in combating oxidative stress-related diseases.
  • Structure-Activity Relationship: Researchers often explore how modifications to the isopropylamino or hydroxy groups can influence the compound's efficacy and potency, providing valuable insights for synthetic chemists.
  • Plant-Derived Insights: The compound’s phenolic nature allows for discussions on its presence and role in various plants, where phenolics are often linked to protection against pathogens.

In conclusion, the study of 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone not only enhances our understanding of chemical properties but also furthers our knowledge in medicinal chemistry and biological systems. As the field evolves, this compound may open doors to innovative therapeutic avenues and contribute to advancements in health science.

Synonyms
Isoproterenone
121-28-8
Aludrone
N-Isopropylnoradrenalone
1-(3,4-dihydroxyphenyl)-2-(propan-2-ylamino)ethanone
1-(3,4-DIHYDROXYPHENYL)-2-[(1-METHYLETHYL)AMINO]ETHAN-1-ONE
S 35179
ACETOPHENONE, 3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-
299T6A9WRP
CHEMBL598662
Ethanone, 1-(3,4-dihydroxyphenyl)-2-((1-methylethyl)amino)-
NSC-163353
Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-
3,4-Dihydroxy-.alpha.-isopropylaminoacetophenone
1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone
1-(3,4-dihydroxyphenyl)-2-[(propan-2-yl)amino]ethan-1-one
1-(3,4-Dihydroxyphenyl)-2-((1-methylethyl)amino)ethan-1-one
1-(3,4-DIHYDROXYPHENYL)-2-((1-METHYLETHYL)AMINO)ETHANONE
EINECS 204-461-0
NSC 163353
BRN 2105828
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone
MLS-0315678.0001
3,4-Dihydroxy-alpha-isopropylaminoacetophenone
3',4'-Dihydroxy-2-(isopropylamino)acetophenone
UNII-299T6A9WRP
4-14-00-00835 (Beilstein Handbook Reference)
SCHEMBL9768178
4-(isopropylaminoacetyl)catechol
BDBM46041
cid_2830496
DTXSID90153099
BBL029136
NSC163353
STL372881
AKOS015955777
CS-0324795
NS00023958
Acetophenone,4'-dihydroxy-2-(isopropylamino)-
S-35179
1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethan-1-one
Ethanone,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-
ISOPRENALINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]
1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone;hydrochloride
1-(3,4-dihydroxyphenyl)-2-(propan-2-ylamino)ethanone;hydrochloride
1-(3,4-dihydroxyphenyl)-2-[(propan-2-yl)amino]ethan-1-one, 3
1-[3,4-bis(oxidanyl)phenyl]-2-(propan-2-ylamino)ethanone;hydrochloride