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Uridine

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Identification
Molecular formula
C9H12N2O6
CAS number
58-96-8
IUPAC name
1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
State
State

At room temperature, Uridine is a solid. It maintains its structural integrity under standard conditions and does not exist as a liquid or gas under normal circumstances.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
244.20g/mol
Molar mass
244.2010g/mol
Density
1.7265g/cm3
Appearence

Uridine appears as white odorless crystalline powder. It is hydrophilic and readily dissolves in water. Due to its chemical structure, it has a relatively high melting point compared to more volatile organic compounds.

Comment on solubility

Solubility of 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione

The compound 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione (C9H12N2O6) exhibits some interesting solubility characteristics worthy of discussion.

Factors Influencing Solubility

Several factors contribute to the solubility of this compound:

  • Hydroxyl Groups: The presence of multiple hydroxyl (-OH) groups enhances hydrogen bonding, which generally increases solubility in polar solvents, such as water.
  • Molecular Structure: The tetrahydrofuran ring imparts some degree of stability and may influence how the compound interacts with solvents.
  • Ionization: Depending on the pH of the solution, certain functional groups may ionize, affecting solubility significantly.

Solubility Profile

While specific solubility data in various solvents can be complex, it is typically observed that:

  • Highly soluble in water due to the polar nature of the hydroxyl groups.
  • Moderately soluble in organic solvents like ethanol or methanol, demonstrating variable solubility characteristics.
  • Practical use: If exploring applications, knowing the solubility in biological systems can be crucial for pharmaceutical relevance.

In summary, understanding the solubility of 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione offers insights into its potential applications and interactions in different environments.

Interesting facts

Interesting Facts about 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione

This compound is a fascinating example of how complex structures can emerge from simple building blocks. Here are some intriguing aspects that highlight its significance:

  • Biological Relevance: This compound closely resembles nucleobases that play crucial roles in various biological processes, particularly in the realm of genetics, where they contribute to DNA and RNA synthesis.
  • Structural Features: The structure of this compound includes both a pyrimidine ring and a sugar moiety, which suggests its potential role in the modification of nucleic acids or as a nucleoside analogue.
  • Antioxidant Potential: The presence of multiple hydroxyl groups within its structure may contribute to antioxidant activities, making it a subject of interest in nutritional and medicinal chemistry.
  • Research Applications: Scientists are constantly investigating compounds like this one for their potential therapeutic applications, such as antiviral and anticancer properties. Its unique structure may inhibit certain metabolic pathways in pathogens or cancer cells.

In the words of renowned chemist, "Nature is a chemist that knows how to make everything with the simplest ingredients." This compound exemplifies this idea, demonstrating the beauty and complexity that arises from the combination of simple molecular fragments.

Overall, the investigation of 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione presents an exciting opportunity for researchers looking to unveil the mysteries of biochemical interactions and potential therapeutic applications.

Synonyms
40436-51-9
1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
Arabinosyluracil
Uracil, 1-.beta.-D-ribofuranosyl-
Uridine-5,6-d2
1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
[5',5''-2H2]uridine
1-(beta-d-xylofuranosyl)uracil
1-(3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
TGBA01AD
MFCD02683606
1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione
Uridine-5-d
40632-21-1
?-D-Uridine
starbld0037839
Diquafosol Impurity-URD
1-.beta.-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione
NCIOpen2_003486
Oprea1_327785
MLS006011814
1-(?-D-Ribofuranosyl)uracil
CHEMBL68846
SCHEMBL2056758
Uracil-1-b-D-arabinofuranoside
SCHEMBL20987631
1.beta.-D-Arabinofuranosyluracil
DTXSID80861595
1-.beta.-D-Arabinofurnosyluracil
1-[(2R,3S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
CHEBI:143353
DRTQHJPVMGBUCF-UHFFFAOYSA-N
Uracil-.beta.-D-arabinofuranoside
HMS3371H19
HMS3655F11
1-((2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
1-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
CIA40684
NSC68928
BBL012100
NSC240592
STK042764
1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
AKOS000493532
AKOS022061523
NR31832
NSC-240592
NCGC00263514-03
NCI60_001702
NCI60_032162
SMR000677923
SY005419
SY038117
SY116434
SY294272
VS-03200
DB-124994
EU-0068295
2,4(1H,3H)-Pyrimidinedione, 1-pentofuranosyl-
EN300-1073139
L000879
.beta.-D-Ribofuranoside,4(1H,3H)-pyrimidinedione-1
2,3H)-Pyrimidinedione, 1-.beta.-D-arabinofuranosyl-
4D6A0DD6-B853-4420-A110-ADA0BAEE9EA7
1-((3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
1-[(2S,3S,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furyl]pyrimidine-2,4(1H,3H)-dione
688007-27-4