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Nicotinamide riboside

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Identification
Molecular formula
C11H15N2O5
CAS number
1341-23-7
IUPAC name
1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyridin-1-ium-3-carboxamide
State
State

At room temperature, nicotinamide riboside is typically found as a solid. It should be stored in a cool, dry place to maintain its stability and prevent it from absorbing moisture from the environment.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.15
Boiling point (Celsius)
346.85
Boiling point (Kelvin)
620.00
General information
Molecular weight
255.24g/mol
Molar mass
255.2410g/mol
Density
1.4395g/cm3
Appearence

Nicotinamide riboside appears as an off-white to pale yellow crystalline powder. It is often found in crystalline form and can be somewhat hygroscopic, meaning it can absorb moisture from the air. This compound is generally not distinguishable from other similar compounds by visual inspection alone without specific chemical tests.

Comment on solubility

Solubility of 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyridin-1-ium-3-carboxamide (C11H15N2O5)

The solubility of 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyridin-1-ium-3-carboxamide is influenced by its unique molecular structure, which incorporates both polar and non-polar functional groups. This duality often leads to interesting solubility characteristics.

In general, the solubility can be summarized as follows:

  • Polar Solvents: This compound is likely to have good solubility in polar solvents, such as water or methanol, due to the presence of hydroxyl (-OH) groups that can form hydrogen bonds.
  • Non-Polar Solvents: Its solubility in non-polar solvents, like hexane or toluene, may be limited owing to the lack of non-polar segments in the molecule.
  • Temperature Effects: Higher temperatures may enhance solubility, especially in polar solvents, as kinetic energy increases and allows for better interaction between solute and solvent.

As a rule of thumb: "Like dissolves like." So, the polarity of the solvent plays a crucial role in the dissolution of this compound.

Further studies are necessary to determine specific solubility parameters such as solubility product and the exact temperature-dependence behavior, which could reveal more about the nature of interactions in solution.

Interesting facts

Interesting Facts about 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyridin-1-ium-3-carboxamide

This intriguing compound, often abbreviated in scientific discussions, combines the versatility of pyridinium and a tetrahydrofuran structure, leading to a variety of applications and unique properties. Here are some noteworthy aspects:

  • Structural Complexity: The presence of both a pyridine ring and a tetrahydrofuran moiety illustrates the compound's structural diversity, allowing it to exhibit unique chemical behavior.
  • Functional Groups: The compound features multiple hydroxyl groups, which enhance its solubility and reactivity. Hydroxyl groups are known for their ability to participate in hydrogen bonding, which can greatly affect solubility and stability.
  • Biological Significance: Compounds like this one can play crucial roles in biological systems. Their structures can lead to potential pharmaceutical applications, especially in targeted drug delivery systems and as enzyme inhibitors.
  • Potential for Synthesis: The synthesis of this compound opens avenues for exploring other derivatives, which might have even more desirable properties or enhanced biological activity.
  • Research and Development: Ongoing research into compounds similar to this one highlights their potential in fields such as materials science, medicinal chemistry, and agrochemicals. Their multifaceted nature can lead to innovations in multiple disciplines within chemistry.

In the words of famous chemist, Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This compound exemplifies that notion, showcasing how chemical structures harbor vast possibilities for exploration and innovation!

Synonyms
SCHEMBL2549414
DTXSID20862647
BCP06938
MFCD16621007
NSC358284
1-(|A-D-ribofuranosyl)-nicotinamide
BCP06938-1
NSC-358284
SY226268
3-Carbamoyl-1-pentofuranosylpyridin-1-ium
NS00122559
Nicotinamide ribose; Nicotinamide-beta-riboside; SRT647; SRT-647; SRT 647
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1,2-dihydropyridine-3-carboxamide;Nicotinamide ribose; Nicotinamide riboside; ribonucleoside