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Uridine

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Identification
Molecular formula
C9H12N2O6
CAS number
58-96-8
IUPAC name
1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-dione
State
State

At room temperature, uridine is typically in a solid crystalline form.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
900.00
Boiling point (Kelvin)
1 173.00
General information
Molecular weight
244.20g/mol
Molar mass
244.2010g/mol
Density
1.7808g/cm3
Appearence

Uridine appears as a white, crystalline powder. It is soluble in water and may form a colorless solution upon dissolution.

Comment on solubility

Solubility of 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-dione

This compound, with the chemical formula C9H12N2O6, showcases intriguing solubility characteristics attributed to its complex molecular structure.

Key Points on Solubility:

  • Polar Functional Groups: The presence of multiple hydroxyl (-OH) groups enhances its polarity, suggesting that the compound is likely to be soluble in polar solvents like water.
  • Hydrogen Bonding: The ability of these -OH groups to form hydrogen bonds can significantly improve solubility in aqueous environments.
  • Solid-State Interactions: In solid states, strong intermolecular forces might hinder solvation, potentially affecting the dissolution process.
  • pH Dependence: Solubility may also vary with changes in pH, as the ionization of certain functional groups could play a role in solubility dynamics.

In summary, while the compound exhibits promising solubility in polar solvents due to its functional group composition, practical solubility must be ascertained under specific conditions. As with many organic compounds, understanding the subtle balance of interaction forces is key to predicting its behavior in various solvent environments.

Interesting facts

Interesting Facts about 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-dione

This compound is an intriguing example of organic chemistry, showcasing a complex structure that incorporates elements typically found in both sugars and nucleobases. Here are some notable aspects that highlight its significance:

  • Structural Composition: The compound features a pyrimidine ring, which is a crucial structural motif found in several biological molecules, including DNA and RNA. This similarity underscores the potential biological activity of this compound.
  • Hydroxyl Groups: The presence of multiple hydroxyl groups (-OH) contributes to the compound's reactivity and solubility, making it a subject of interest in biochemical studies and potential applications in medicinal chemistry.
  • Sugar-like Structure: The tetrahydrofuran moiety, a saturated cyclic ether, suggests that this compound may possess characteristics similar to carbohydrate compounds, hinting at roles in cellular processes or metabolism.
  • Potential Biological Activity: Compounds with both hydroxymethyl and hydroxyl functionalities are often explored for their biochemical roles. This may include antioxidant properties or serving as precursors in biochemical pathways, enhancing its importance in pharmaceutical research.
  • Research Implications: Understanding this compound can lead to the development of new therapeutic agents. Its unique combination of features may be useful in targeting specific biological receptors or as a building block in drug design.

In summary, 1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-dione stands as a testament to the intricate connections between structure and function in organic chemistry. Its unique features open doors to further research and potential applications in various fields.

Synonyms
69321-95-5
OHUrd
1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidine-2,4-dione
1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-1,2,3,4-tetrahydropyrimidine-2,4-dione
4,5-dihydroxy-1-pentofuranosylpyrimidin-2(1H)-one
SCHEMBL18513006
NSC117925
STK680995
AKOS005596111
NSC-117925
DB-057606
SR-01000091487
SR-01000091487-1
1-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-hydroxypyrimidine-2,4(1H,3H)-dione;ST082427