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1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline

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Identification
Molecular formula
C26H31NO4
CAS number
.null
IUPAC name
1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline
State
State

It is a solid at room temperature, typically existing as a powder with a yellow hue.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
442.00
Boiling point (Kelvin)
715.15
General information
Molecular weight
383.48g/mol
Molar mass
383.4820g/mol
Density
1.2234g/cm3
Appearence

This compound typically appears as a yellow crystalline solid, although exact appearance can vary slightly depending on purity and other factors.

Comment on solubility

Solubility of 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline

The solubility of 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline (C26H31NO4) can be an intriguing subject due to its complex structure and substituents. Here are some key points regarding its solubility:

  • Polarity: The presence of ethoxy groups in the molecule suggests an increased level of hydrophobic characteristics, which might limit its solubility in polar solvents.
  • Solvent Compatibility: This compound may show improved solubility in organic solvents such as ethanol, methanol, or chloroform, rather than in water, due to its large hydrocarbon portion.
  • Temperature Dependence: Like many organic compounds, its solubility may increase with temperature, making hot solvents a better choice for dissolving this isoquinoline derivative.
  • Crystallinity: If the compound exhibits high crystallinity, this may also impede solubility and require specific conditions to achieve a satisfactory dissolution.

In conclusion, while 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline might not be readily soluble in water, utilizing organic solvents, particularly under heated conditions, can enhance its solubility profile.

Interesting facts

Interesting Facts about 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline

This compound holds a unique position in the realm of organic chemistry due to its intricate structure and potential applications. Here are some fascinating insights:

  • Complex Structure: The molecule features an isoquinoline core, which is a bicyclic structure known for its diverse biological activities.
  • Substituents Matter: The presence of diethoxy groups at the 6 and 7 positions enhances the compound's lipophilicity, making it potentially more effective in penetrating biological membranes.
  • Pharmacological Interest: Compounds like this one are studied for their possible anti-cancer and anti-inflammatory properties, showing promise in drug development.
  • Synthetic Challenges: The synthesis of such compounds can be intricate and may involve multiple steps, often requiring careful control of reaction conditions to avoid side products.

As emphasized by scientists in the field, “The exploration of novel isoquinoline derivatives provides a vast landscape for discovering new pharmacophores.” This statement underlines the importance of compounds like 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline in medicinal chemistry.

Furthermore, ongoing research is likely to reveal more about the mechanisms of action and potential therapeutic targets for compounds in this class, making them an exciting topic of exploration for both students and experienced chemists alike.

Synonyms
ethaverine
Ethylpapaverine
Barbonin
Barbonine
Dyscural
486-47-5
Ethquinol
Perparine
Perperine
Ethaverine [INN]
Etaverina
Ethaverinum
Etaverina [INN-Spanish]
Ethaverinum [INN-Latin]
1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline
1-(3,4-Diethoxybenzyl)-6,7-diethoxyisoquinoline
6,7-Diethoxy-1-(3,4-diethoxybenzyl)isoquinoline
UNII-2H2HC19DYZ
EINECS 207-633-3
2H2HC19DYZ
Ethquinol (TN)
Ethaverine (INN)
BRN 0342349
Isoquinoline, 6,7-diethoxy-1-(3,4-diethoxybenzyl)-
ETHAVERINE [MI]
ISOQUINOLINE, 1-(3,4-DIETHOXYBENZYL)-6,7-DIETHOXY-
ETHAVERINE [VANDF]
6,7-Diaethoxy-1-(3,4-diaethoxybenzyl)isochinolin
ETHAVERINE [WHO-DD]
6,7-Diaethoxy-1-(3,4-diaethoxybenzyl)isochinolin [German]
DTXSID3023009
Isoquinoline, 1-((3,4-diethoxyphenyl)methyl)-6,7-diethoxy-
Isoquinoline, 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-
5-21-06-00183 (Beilstein Handbook Reference)
1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline
Etaverina (INN-Spanish)
Ethaverinum (INN-Latin)
NCGC00016557-01
CAS-985-13-7
1-((3,4-diethoxyphenyl)methyl)-6,7-diethoxyisoquinoline
Spectrum_001218
Prestwick0_000830
Prestwick1_000830
Prestwick2_000830
Prestwick3_000830
Spectrum2_001385
Spectrum3_001425
Spectrum4_000406
Spectrum5_001524
SCHEMBL25606
BSPBio_000759
BSPBio_003130
KBioGR_000672
KBioSS_001698
DivK1c_000199
SPBio_001370
SPBio_002680
BPBio1_000835
DTXCID903009
CHEMBL1555736
CHEBI:94592
KBio1_000199
KBio2_001698
KBio2_004266
KBio2_006834
KBio3_002350
NINDS_000199
EX-A5513
1-{[3,4-bis(ethyloxy)phenyl]methyl}-6,7-bis(ethyloxy)isoquinoline
AKOS024366261
IDI1_000199
NCGC00016557-02
NCGC00016557-03
SBI-0051627.P002
AB00053589
NS00004322
D07926
AB00053589_04
BRD-K36756879-003-05-3
BRD-K36756879-003-06-1
BRD-K36756879-003-08-7
Q27166421
Isoquinolinium, 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-
Isoquinoline, 1-((3,4-diethoxyphenyl)methyl)-6,7-diethoxy-(9CI)
207-633-3
VIC