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Propranolol

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Identification
Molecular formula
C13H21Cl2NO2
CAS number
318-98-9
IUPAC name
1-(3,4-dichlorophenyl)-2-(isopropylamino)ethanol
State
State

Propranolol is usually found in a solid state at room temperature, most commonly available in tablets or capsules when prescribed as medication.

Melting point (Celsius)
97.00
Melting point (Kelvin)
370.15
Boiling point (Celsius)
110.00
Boiling point (Kelvin)
383.15
General information
Molecular weight
295.81g/mol
Molar mass
295.8070g/mol
Density
1.2000g/cm3
Appearence

Propranolol is a white to off-white crystalline powder. It is odorless and has a bitter taste. The compound is often found in tablet forms when used for medicinal purposes.

Comment on solubility

Solubility of 1-(3,4-dichlorophenyl)-2-(isopropylamino)ethanol (C13H21Cl2NO2)

The solubility of 1-(3,4-dichlorophenyl)-2-(isopropylamino)ethanol in various solvents is a noteworthy aspect of this compound's characteristics. This compound encompasses different functional groups that influence its interaction with solvents, primarily

  • **Chlorinated aromatic ring** - enhances its potential for solubility in organic solvents.
  • **Amine and alcohol functionalities** - improve affinity for polar solvents such as water.

Generally, one can theorize the solubility based on structural features, and this compound is expected to exhibit:

  • Moderate solubility in water due to the presence of the hydroxyl (-OH) group.
  • Higher solubility in organic solvents like ethanol, methanol, and acetone because of its hydrophobic aromatic ring.

As with many organic compounds, factors affecting solubility include:

  • Temperature: Increased temperature often leads to increased solubility.
  • pH Level: Changes in pH can affect the ionization of the amine group, further influencing solubility.

In conclusion, while the solubility profile is complex and influenced by multiple factors, understanding these interactions is essential for effective application and utilization of 1-(3,4-dichlorophenyl)-2-(isopropylamino)ethanol.

Interesting facts

Interesting Facts About 1-(3,4-dichlorophenyl)-2-(isopropylamino)ethanol

1-(3,4-dichlorophenyl)-2-(isopropylamino)ethanol, commonly known as Phenelzine, is a fascinating compound with unique properties and applications in the field of medicinal chemistry. Here are some noteworthy aspects to consider:

  • Pharmacological Significance: This compound is primarily recognized for its role as a monoamine oxidase inhibitor (MAOI) and has been used in the treatment of depression and anxiety disorders.
  • Chemical Structure: The presence of both a dichlorophenyl group and an isopropylamino side chain significantly influences the compound's activity, making it a valuable structure in drug design.
  • Mechanism of Action: As an MAOI, it functions by inhibiting the enzyme monoamine oxidase, which is responsible for breaking down neurotransmitters in the brain. This leads to increased levels of essential neurotransmitters such as serotonin and norepinephrine.
  • Side Effects and Considerations: While effective, it requires careful dietary management to avoid potential interactions with tyramine-rich foods, which can lead to hypertensive crises.
  • Cultural Impact: Its use in psychopharmacology and the treatment of mental health conditions has opened discussions regarding the stigma of mental illness and the importance of research in this area.

In summary, the study of 1-(3,4-dichlorophenyl)-2-(isopropylamino)ethanol not only contributes to our understanding of pharmacology but also underlines the complexity and significance of developing effective treatment options for mental health disorders. As noted by researchers, "Understanding compounds like these can lead to breakthroughs in how we approach mental health care."

Synonyms
Dichloroisoproterenol
59-61-0
Dichlorisoproterenol
Dichlorisoprenaline
1-(3,4-Dichlorophenyl)-2-isopropylaminoethanol
Dichlorisoprenaline [German]
3,4-Dichlor-isoproterenol [German]
3,4-Dichlor-isoproterenol
U7NOE2K4M2
BRN 2807251
1-(3,4-dichlorophenyl)-2-(propan-2-ylamino)ethanol
beta-Hydroxy-N-isopropyl-3,4-dichlorophenethylamine
CHEMBL30816
3,4-Dichloro-alpha-(isopropylaminomethyl)benzyl alcohol
N-(beta-(3,4-Dichlorophenyl)-beta-hydroxyethyl)isopropylamine
3,4-Dichloro-alpha-(((1-methylethyl)amino)methyl)benzenemethanol
DTXSID20874225
(+/-)-DICHLORISOPROTERENOL
Dichloroisoprenaline
BENZYL ALCOHOL, 3,4-DICHLORO-alpha-((ISOPROPYLAMINO)METHYL)-
L-20522
DCI
BENZENEMETHANOL, 3,4-DICHLORO-.ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)-
UNII-U7NOE2K4M2
1-(3,4-dichlorophenyl)-2-((propan-2-yl)amino)ethan-1-ol
1-(3,4-dichlorophenyl)-2-[(propan-2-yl)amino]ethan-1-ol
1-(3,4-dichlorophenyl)-2-(propan-2-ylamino)ethanol hydrochloride
Dichloroisoproterenol,(+/-)
1-(3,4-Dichlorophenyl)-2-(isopropylamino)ethanol
SCHEMBL613952
VKMGSWIFEHZQRS-UHFFFAOYSA-
VKMGSWIFEHZQRS-UHFFFAOYSA-N
DTXCID601012357
BDBM50036835
PDSP1_000154
PDSP2_000153
AKOS009157165
DB12803
2-isopropylamino-1-(3,4-dichlorophenyl)-ethanol
2-isopropylamino-1-(3,4-dichlorophenyl)ethanol
1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol
Q387276
benzene, 1,2-dichloro-4-(1-hydroxy-2-isopropylamino)ethyl-
1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol(Di chloroisoproterenol)
BENZENEMETHANOL, 3,4-DICHLORO-ALPHA-(((1-METHYLETHYL)AMINO)METHYL)-
InChI=1/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3