Interesting facts
Interesting Facts about 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-3H-isobenzofuran-5-carbonitrile
This intriguing compound, often referred to in the scientific community for its unique structure, combines several functional groups that contribute to its reactivity and potential applications. Here are some engaging facts about this fascinating molecule:
- Structural Complexity: The compound features a complex backbone characteristic of isobenzofuran structures, which are known for their interesting electronic properties and biological activities.
- Fluorine's Role: The presence of the fluorine atom not only influences the compound's physical properties but also enhances its lipophilicity, potentially improving its membrane permeability and biological activity.
- Biological Implications: Compounds of this nature may exhibit pharmacological properties, especially in the domains of antitumor and antidepressant activities, due to their ability to interact with various receptors in biological systems.
- Diverse Functional Groups: The inclusion of the dimethylamino group allows for interesting chemical reactivity while also serving as a site for potential biological interactions, which could lead to the development of novel therapeutic agents.
- Application in Research: Scientists are keenly interested in exploring compounds like this one to gain insights into drug design and development, particularly in creating more selective and effective agents targeted at specific diseases.
As a chemist, one cannot help but appreciate the intricate relationships between a compound's structure and its potential applications in various fields, such as medicinal chemistry and organic synthesis. Understanding and exploring these relationships can lead to groundbreaking advancements in drug discovery and material science.
Synonyms
citalopram
59729-33-8
Nitalapram
Cipram
Celexa
Citalopramum
Citadur
Citalopramum [INN-Latin]
Bonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
[3H]Citalopram
1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
Lu 10-171
UNII-0DHU5B8D6V
EINECS 261-891-1
0DHU5B8D6V
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
Lu-10-171
CHEMBL549
Citalopram [USP:INN:BAN]
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile
5-Isobenzofurancarbonitrile,1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-
Cytalopram
DTXSID8022826
CHEBI:77397
HSDB 7042
LU-10171B
5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-
[3H]-Citalopram
Citalopramum (INN-Latin)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-isobenzofuran-5-carbonitrile
CITALOPRAM (MART.)
CITALOPRAM [MART.]
5-Isobenzofurancarbonitrile, 1,3-dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-
5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-
Citalopram (USP:INN:BAN)
CITALOPRAM (USP IMPURITY)
CITALOPRAM [USP IMPURITY]
Perrigo citalopram
SMR000465669
Citadur (TN)
Citalopram (USP/INN)
1-[3-(dimethylamino)propyl]-1-(p-fluorophenyl)-5-phthalancarbonitrile
[3H]Cytalopram
[3H]Escitalopram
[3H]Lexapro
(+/-)-citalopram
Citalopramum (Latin)
CITALOPRAM [MI]
CITALOPRAM [INN]
Prestwick3_000692
SCHEMBL946
CITALOPRAM [VANDF]
CITALOPRAM [WHO-DD]
Lopac0_000258
BSPBio_000843
AE-641/00603021
MLS000028578
MLS006011858
BPBio1_000929
CHEBI:3723
DTXCID802826
GTPL4621
GTPL7547
BDBM25870
WSEQXVZVJXJVFP-UHFFFAOYSA-
N06AB04
PS18 - Citalopram/Norcitalopram
HMS2090O09
HMS2093A14
HMS3259B10
QXB00326
UYB90884
BBL029066
STL058639
AKOS005711003
AC-8894
CCG-204353
DB00215
NC00711
SDCCGSBI-0050246.P003
1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carb onitrile
MRF-0000302
NCGC00015267-04
NCGC00015267-05
NCGC00015267-07
NCGC00015267-09
NCGC00015267-11
NCGC00015267-12
NCGC00015267-20
NCGC00015267-26
NCGC00025160-02
AS-76503
SBI-0050246.P002
HY-121203
AB00513896
C3149
CS-0081223
NS00000035
C07572
D07704
EN300-304884
AB00513896-09
AB00513896-11
AB00513896_12
AB00513896_13
A832440
AE-641/00605044
L001223
Q409672
SR-01000003129-8
BRD-A47598013-004-02-0
BRD-A47598013-004-06-1
BRD-A47598013-004-16-0
BRD-A47598013-004-17-8
BRD-A47598013-004-18-6
BRD-A47598013-034-02-7
1-(3'-dimethylaminopropyl)-1-(4'-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
1-(3-(dimethylamino)propyl)-1-(4'-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
1-(3-Dimethylamino-propyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-5-carbonitrile
1-[3-(dimethylamino) propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro[3,4]benzofuran-5-carbonitrile
5-Cyano-1-(4-fluorophenyl)-1-(3-dimethylaminopropyl)-1,3-dihydro-isobenzofuran
rac-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
261-891-1
InChI=1/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
Solubility of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-isobenzofuran-5-carbonitrile
The solubility of the compound 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-isobenzofuran-5-carbonitrile (C20H21FN2O) can be influenced by various factors due to its complex structure. Here are some pertinent points to consider:
In summary, the solubility of this compound is likely to be moderate and influenced by the balance of hydrophilic and hydrophobic interactions, solvent choice, and environmental conditions. Future investigations into its solubility profile would be useful for practical applications and formulation purposes.