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Thioflavin T

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Identification
Molecular formula
C17H19NO2S
CAS number
2390-54-7
IUPAC name
1-[3-(diethylamino)propylamino]-4-(hydroxymethyl)thioxanthen-9-one
State
State

At room temperature, Thioflavin T is a crystalline solid.

Melting point (Celsius)
221.00
Melting point (Kelvin)
494.15
Boiling point (Celsius)
388.50
Boiling point (Kelvin)
661.70
General information
Molecular weight
401.55g/mol
Molar mass
401.5460g/mol
Density
1.3490g/cm3
Appearence

The compound is typically a yellow to yellow-green crystalline powder. It is known for its ability to fluoresce under ultraviolet light, producing a bright yellow fluorescence.

Comment on solubility

Solubility of 1-[3-(diethylamino)propylamino]-4-(hydroxymethyl)thioxanthen-9-one

The solubility of the compound 1-[3-(diethylamino)propylamino]-4-(hydroxymethyl)thioxanthen-9-one (C17H19NO2S) can exhibit interesting characteristics due to its unique structure.

  • Polarity: The presence of both amino groups and hydroxymethyl functional groups suggests that the compound may possess polar characteristics, which can enhance its solubility in polar solvents such as water and alcohols.
  • Hydrophobicity: The thioxanthen scaffold contributes a degree of hydrophobicity, which might affect solubility in non-polar solvents.
  • Potential Solvents:
    • Water
    • Ethanol
    • Acetonitrile
  • Influence of pH: The solubility may be pH-dependent, particularly due to the presence of the amino groups, which could interact with protons in acidic or basic conditions.

In conclusion, the solubility of this compound may vary significantly based on its medium, highlighting the importance of considering both structural features and environmental conditions. Further experimental solubility data would provide a more comprehensive understanding of its behavior in different solvents.

Interesting facts

Interesting Facts about 1-[3-(diethylamino)propylamino]-4-(hydroxymethyl)thioxanthen-9-one

This fascinating compound, often abbreviated as DT-13, is part of a class of chemical entities known for their broad applications in medicinal chemistry and materials science. Here are some intriguing tidbits:

  • Structural Diversity: The compound features both a thioxanthene core and a diethylamino substituent, showcasing a remarkable structural diversity that can facilitate interactions with biological targets.
  • Pharmacological Potential: Studies have indicated that compounds like DT-13 may exhibit significant pharmacological properties, including potential anti-cancer and anti-inflammatory activities, making it a subject of interest in drug development.
  • Mechanisms of Action: The specific interactions of DT-13 with cellular receptors are an area of ongoing research, emphasizing the importance of understanding structure-activity relationships in designing effective therapeutics.
  • Research Applications: Compounds of this kind serve as useful tools in chemical biology, particularly in probing cellular pathways and mechanisms, which are crucial for therapeutic advancements.
  • Colorimetric Applications: Due to its unique structural attributes, it may also find usage in designing colorimetric sensors, thus expanding its applicability beyond just medicinal chemistry.

As scientists and students delve into the chemistry of DT-13, it’s essential to consider not just its molecular structure but the potential it holds for contributions to science and medicine. As expressed by many in the field, “The discovery lies not only in the chemical itself but in the myriad of possibilities it presents for innovation.”

Synonyms
SCHEMBL6558809
CHEMBL5488003
FHLGVCDHQRZXMB-UHFFFAOYSA-N
1-[[3-(diethyiamino)propyl]amino]-4-(hydroxymethyl) thioxanthen-9-one
1-[[3-(Diethylamino)propyl]amino]-4-(hydroxymethyl)-thioxanthen-9-one
1-[[3-(diethylamino)propyl]amino]-4-(hydroxymethyl)thioxanthen-9-one