Interesting facts
Interesting Facts About 1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethyl-ethyl)amino]propan-1-one
This compound is a fascinating example of modern medicinal chemistry, reflecting the intricate balance between structure and function in pharmaceutical design. Here are some noteworthy points:
- Pharmacological significance: The compound is noted for its potential analgesic and anti-inflammatory properties, which are essential in the development of new pain management therapies.
- Structural Diversity: Its unique structure features a chlorophenyl group, which often plays a crucial role in influencing biological activity and pharmacokinetics.
- Synergistic Effect: The presence of both a hydroxyl and amine functional group on the side chain enhances binding interactions with target proteins, potentially leading to improved therapeutic effects.
- Research Focus: This compound has attracted interest in academic and industrial labs alike, driving research into its mechanism of action and developing derivatives that may offer better efficacy or safety profiles.
- Chlorine's Role: The chlorine atom not only contributes to the compound's lipophilicity but also affects its electronic properties, possibly altering affinity and selectivity towards biological targets.
In summary, 1-(3-chlorophenyl)-2-[(2-hydroxy-1,1-dimethyl-ethyl)amino]propan-1-one exemplifies the art and science of drug design, where every atom and bond can significantly influence the compound's behavior in biological systems. As research continues, we may unlock even more possibilities for this intriguing molecular framework.
Synonyms
hydroxybupropion
92264-81-8
Hydroxybupropione
1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one
6-Hydroxybupropion
Hydroxybupropion, (+/-)-
BW-306U
DTXSID101002894
V94F513635
1-Propanone, 1-(3-chlorophenyl)-2-((2-hydroxy-1,1-dimethylethyl)amino)-
1-(3-chlorophenyl)-2-((1-hydroxy-2-methylpropan-2-yl)amino)propan-1-one
Hydroxybupropion?
UNII-V94F513635
82793-84-8
SCHEMBL1226857
CHEMBL3544616
US9333197, Hydroxybupropion
AKOAEVOSDHIVFX-UHFFFAOYSA-N
CHEBI:166487
BDBM224811
DTXCID401429823
SDA26481
1-(3-chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone
AKOS040733401
Hydroxybupropion, 1mg/ml in Acetonitrile
1ST11043
DA-54164
TS-07818
HY-100637
CS-0019871
NS00078045
G91175
Q18206601
1-(3-chlorophenyl)-2-(1-hydroxy-2-methylpropan-2-ylamino)propan-1-one
2-(1-hydroxy-2-methylpropan-2-ylamino)-1-(3-chlorophenyl)propan-1-one
686-870-8
Solubility of 1-(3-chlorophenyl)-2-[(2-hydroxy-1,1-dimethyl-ethyl)amino]propan-1-one
The solubility of the compound 1-(3-chlorophenyl)-2-[(2-hydroxy-1,1-dimethyl-ethyl)amino]propan-1-one (C16H19ClNO2) can be influenced by several key factors:
However, it's important to note that due to the presence of a bulky dimethyl group and other substituents, the solubility may vary widely. Therefore, it is recommended to conduct solubility tests in specific solvents to determine its practical solubility characteristics. As a rule of thumb, “like dissolves like,” meaning that understanding the solvent's polarity in relation to the compound can provide insights into its solubility behavior.