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Glutamyl - Pyrrolidinone Carboxylic Acid

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Identification
Molecular formula
C9H13N2O5
CAS number
.
IUPAC name
1-(3-carboxypropanoyl)pyrrolidine-2-carboxylic acid
State
State

The compound is a solid at room temperature, typically forming white or off-white crystals. Its crystalline nature aids in its stability and shelf storage.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
197.19g/mol
Molar mass
197.1880g/mol
Density
1.4600g/cm3
Appearence

The compound is generally a white crystalline solid that is characterized by its ability to form strong hydrogen bonds, making it slightly soluble in water.

Comment on solubility

Solubility of 1-(3-carboxypropanoyl)pyrrolidine-2-carboxylic acid

The compound 1-(3-carboxypropanoyl)pyrrolidine-2-carboxylic acid, with the chemical formula C9H13N2O5, exhibits interesting solubility characteristics that can be influenced by various factors. Here are some key points to consider regarding its solubility:

  • Polar Functional Groups: The presence of multiple carboxylic acid groups in the structure suggests that this compound is likely to be polar, which can enhance its solubility in polar solvents like water.
  • Hydrogen Bonding: The carboxylic groups can engage in hydrogen bonding with water molecules, further promoting solubility. This interaction may lead to a significantly higher solubility compared to non-polar compounds.
  • pH Sensitivity: The ionization state of the carboxylic acid groups can vary with pH, which means that its solubility may increase in basic conditions due to deprotonation, resulting in more soluble anionic forms.
  • Temperature Dependence: Solubility can also be temperature-dependent. Increasing the temperature may enhance solubility through increased kinetic energy and disruption of intermolecular forces.
  • Comparison to Similar Compounds: When comparing with related amino acids or derivatives, these structural features can often lead to differing solubility profiles, providing insights into the compound's unique behavior.

Given these considerations, it can be concluded that 1-(3-carboxypropanoyl)pyrrolidine-2-carboxylic acid is expected to have a moderate to high solubility in aqueous solutions, especially under certain conditions. However, experimental solubility data would provide the most accurate insights into its solubility behavior.

Interesting facts

Interesting Facts about 1-(3-Carboxypropanoyl)pyrrolidine-2-carboxylic Acid

1-(3-Carboxypropanoyl)pyrrolidine-2-carboxylic acid is a unique compound that provides insight into the interplay between chemical structure and biological function. This compound is particularly fascinating for several reasons:

  • Structure-Activity Relationship: The structural features of 1-(3-carboxypropanoyl)pyrrolidine-2-carboxylic acid lend themselves to significant biological activity. Its ability to act as a natural or synthetic ligand could influence various biochemical pathways.
  • Role in Drug Design: Due to its carboxylic acid moieties, this compound has potential applications in the design of pharmaceuticals. The presence of multiple carboxyl groups can enhance solubility and bioavailability, which are critical features in medicinal chemistry.
  • Biochemical Relevance: Compounds with pyrrolidine structures are often involved in pharmacology and medicinal chemistry. They can exhibit diverse properties, ranging from analgesics to anti-inflammatory agents, making them essential in the development of new therapeutic agents.
  • Synthesis Challenges: The synthesis of such compounds often requires careful planning and execution. Multi-step synthetic routes can be required, which makes studying this compound particularly intriguing for chemistry students looking to engage in complex organic synthesis.

Overall, 1-(3-carboxypropanoyl)pyrrolidine-2-carboxylic acid stands as a reminder of the intricate connections between structure, function, and application in the world of chemical compounds. As researchers continue to explore its properties, this compound may well contribute to advances in drug discovery and development.

Synonyms
N-Succinyl-L-proline
CHEMBL302840
Lopac0_001118
HMS3263O18
HMS3371D02
Tox21_501118
BDBM50046623
AKOS026404411
CCG-205194
LP01118
SDCCGSBI-0051087.P002
NCGC00015960-02
NCGC00015960-03
NCGC00015960-04
NCGC00094388-01
NCGC00094388-02
NCGC00261803-01
EU-0101118
S 6633
SR-01000076134
SR-01000076134-2
1-(3-Carboxy-propionyl)-pyrrolidine-2-carboxylic acid
1-(3-Carboxy-propionyl)-pyrrolidine-2-carboxylic acid(Succinyl-L-proline)