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Uridine

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Identification
Molecular formula
C9H12N2O6
CAS number
58-96-8
IUPAC name
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
State
State

At room temperature, uridine is in a solid state. It is commonly found as a crystalline powder, making it easy to handle and measure in laboratory settings.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
792.60
Boiling point (Kelvin)
1 065.80
General information
Molecular weight
244.20g/mol
Molar mass
244.2040g/mol
Density
1.6422g/cm3
Appearence

Uridine typically appears as a white crystalline powder. Its crystalline structure and relatively high melting point are indicative of its purity and stability at room temperature.

Comment on solubility

Solubility of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione

The compound represented by the formula C9H12N2O6 has complex solubility characteristics influenced by its structural composition. This compound features both hydroxyl groups and a pyrimidine ring, which can significantly affect its interaction with solvents. Let's delve into some key aspects of its solubility:

  • Polarity: The presence of multiple hydroxyl groups suggests that the compound is polar, likely enhancing its solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: Hydroxyl groups enable extensive hydrogen bonding, facilitating better solubility in aqueous solutions. This can lead to increased interactions between the solute and solvent molecules.
  • Solvent Compatibility: The structural features indicate that this compound may have limited solubility in non-polar solvents, such as hexane or benzene. As a general rule, "like dissolves like" — thus polar solvents are preferred for this compound.
  • pH Influence: The pH of the solution can also impact solubility, as the ionization of functional groups may enhance or hinder solubility based on the local environment.

In summary, it can be said that 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione is likely to be soluble in polar solvents due to its structure. However, the exact solubility values can vary based on specific conditions such as temperature and pH. Understanding these parameters is essential for practical applications in fields like pharmaceuticals and biochemistry.

Interesting facts

Interesting Facts about 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione

This compound is a fascinating example of how complex organic molecules can exhibit significant biological activity. Here are some intriguing aspects of this compound:

  • Structural Complexity: The molecule features a pyrimidine ring, which is a key structure in various biological systems, including DNA and RNA. The presence of multiple hydroxyl groups adds to its complexity and potential reactivity.
  • Potential Biological Role: Compounds like this one may possess important biological functions, particularly in the field of medicinal chemistry. Due to its structural components, it may be involved in enzymatic processes or act as a signaling molecule in cellular pathways.
  • Stereochemistry: The specific stereochemistry of this compound is significant. The (2R,3R,4S,5R) configuration influences how the molecule interacts with biological systems, contributing to its overall efficacy and function.
  • Research Applications: Scientists are continuously investigating compounds like this for their potential therapeutic applications. They could potentially lead to the development of new drugs that target various diseases or improve metabolic processes.

As one researcher noted, "Understanding the intricate relationships between structure and function in complex organic molecules is key to unlocking new therapeutic avenues." This compound exemplifies that philosophy, exhibiting a unique blend of structural intricacy and potential utility in the pharmaceutics field.

Overall, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione is more than just a chemical compound; it's a bridge between organic chemistry and biological activity, opening doors to exciting research possibilities.

Synonyms
uridine
58-96-8
Uridin
Uracil riboside
1-beta-D-Ribofuranosyluracil
beta-Uridine
Uracil, 1-beta-D-ribofuranosyl-
d-uridine
CHEBI:16704
MFCD00006526
NSC 20256
1-.beta.-D-Ribofuranosyluracil
AI3-52690
UNII-WHI7HQ7H85
EINECS 200-407-5
Urd
WHI7HQ7H85
Uridine-15N2
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
NSC-20256
MLS000069625
DTXSID40891555
NSC20256
1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione
C9H12N2O6
SMR000058222
92487-68-8
URIDINE (MART.)
URIDINE [MART.]
URIDINE (USP-RS)
URIDINE [USP-RS]
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
URIDINE (USP IMPURITY)
URIDINE [USP IMPURITY]
1-beta-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dione (Uridine)
b-Uridine
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
69-75-0
ADENOSINE IMPURITY F (EP IMPURITY)
ADENOSINE IMPURITY F [EP IMPURITY]
araU
d-Ribosyl uracil
.beta.-Uridine
Uridine,(S)
Uridine (Standard)
1af2
4jx9
4pd6
Opera_ID_118
Uridine, >=99%
URIDINE [MI]
1-b-D-Ribofuranosyluracil
URIDINE [WHO-DD]
1-A-D-Ribofuranosyluracil
bmse000158
bmse000816
bmse000864
Epitope ID:149164
1-.beta.-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione
beta-D-ribofuranosyl-uridine
SCHEMBL20667
Uracil-1-b-D-ribofuranoside
Uracil-1-A-D-ribofuranoside
rg2417
Uridine, BioUltra, >=99%
Uracil-1-beta-d-ribofuranoside
CHEMBL100259
GTPL4566
1-beta-delta-Ribofuranosyluracil
HY-B1449R
Uracil-1-.beta.-d-ribofuranoside
DTXCID001030648
HMS2230P13
HMS3884M20
HY-B1449
BDBM50088517
s2029
AKOS015896922
CCG-214447
CS-5153
DB02745
NU06309
SMP1_000029
NCGC00017312-02
NCGC00017312-04
NCGC00017312-05
NCGC00142368-01
1-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-dihydropyrimi dine-2,4-dione
BP-58653
DS-14345
SRI-10895_12
Uridine, Vetec(TM) reagent grade, 99%
DB-030519
NS00014580
U0020
C00299
EN300-221746
1-b-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione
b-D-Ribofuranoside 2,4(1H,3H)-pyrimidinedione-1
Q422573
BRD-K13050303-001-17-3
BRD-K13050303-001-18-1
Uridine, powder, BioReagent, suitable for cell culture
.beta.-D-Ribofuranoside, 2,4(1H,3H)-pyrimidinedione-1
1-beta-delta-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione
6B6FA3F8-70A2-44EA-B99C-D35D0A9237AA
beta-delta-Ribofuranoside 2,4(1H,3H)-pyrimidinedione-1
Z1741976658
1-.BETA.-D-RIBOFURANOSYLPYRIMIDINE-2,4(1H,3H)-DIONE
1-beta-D-Ribofuranosyluracil, Uracil-1-beta-D-ribofuranoside
1-beta-D-Ribofuranosyluracil; Uracil-1-beta-D-ribofuranoside
Uridine, United States Pharmacopeia (USP) Reference Standard
200-407-5