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2,3-dichloroamphetamine

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Identification
Molecular formula
C8H9Cl2N
CAS number
14100-08-0
IUPAC name
1-(2,3-dichlorophenyl)ethanamine
State
State

At room temperature, 2,3-Dichloroamphetamine is typically found in a solid state, often as a crystalline powder.

Melting point (Celsius)
44.00
Melting point (Kelvin)
317.20
Boiling point (Celsius)
272.50
Boiling point (Kelvin)
545.60
General information
Molecular weight
192.07g/mol
Molar mass
192.0700g/mol
Density
1.3000g/cm3
Appearence

2,3-Dichloroamphetamine typically appears as a crystalline solid. Its color can vary from white to off-white, depending on the purity and specific conditions of synthesis.

Comment on solubility

Solubility of 1-(2,3-dichlorophenyl)ethanamine

The solubility of 1-(2,3-dichlorophenyl)ethanamine (C8H9Cl2N) can be influenced by several factors:

  • Polarity: This compound contains a dichlorophenyl group, which contributes to its overall polarity. Thus, it is expected to be more soluble in polar solvents.
  • Hydrogen Bonding: The presence of the amine group allows the compound to engage in hydrogen bonding, enhancing its solubility in water compared to non-polar solvents.
  • Temperature Effects: Like many organic compounds, solubility can increase with temperature. As the temperature rises, the kinetic energy of molecules increases, potentially overcoming intermolecular forces.

In general, 1-(2,3-dichlorophenyl)ethanamine is anticipated to exhibit moderate solubility in water while being highly soluble in organic solvents such as ethanol or acetone, making it versatile for various applications.

Interesting facts

Exploring 1-(2,3-dichlorophenyl)ethanamine

1-(2,3-dichlorophenyl)ethanamine is a fascinating compound that falls within the realm of organic chemistry, particularly celebrated for its structural complexity and potential applications. Here are some interesting facts that illuminate its significance:

  • Pharmaceutical Relevance: This compound is often studied for its role in the synthesis of pharmaceutical agents, particularly those that target the central nervous system. Its dichloro substitution provides unique electronic properties that can enhance biological activity.
  • Structure-Activity Relationship (SAR): Researchers are particularly interested in the structure-activity relationships of compounds like 1-(2,3-dichlorophenyl)ethanamine. Small changes in structure can lead to significant variations in activity, making it a key subject in medicinal chemistry.
  • Chirality Considerations: The compound can exist as enantiomers, which can exhibit different biological behaviors. Understanding these differences is crucial in drug development and efficacy, making chirality a vital topic in pharmacology.
  • Environmental Impact: The utilization of chlorinated compounds in various industries has raised concerns about environmental persistence. Research on 1-(2,3-dichlorophenyl)ethanamine may contribute to understanding the fate of such chemicals in ecosystems.
  • Research Opportunities: The presence of both chlorines and an amine group opens pathways for further functionalization. Scientists are excited by the possibility of new derivatives leading to novel compounds with enhanced properties.

As we dive deeper into the world of organic compounds like 1-(2,3-dichlorophenyl)ethanamine, we glimpse the intricate dance of atoms and bonds that drives innovation in pharmaceuticals and other vital fields. Such compounds are not merely chemical entities; they represent a bridge between scientific discovery and practical application.

Synonyms
1-(2,3-dichlorophenyl)ethanamine
39226-94-3
1-(2,3-dichlorophenyl)ethan-1-amine
2,3-dichloro-alpha-methylbenzylamine
Lilly 78335
(+/-)-2 3-DICHLORO-ALPHA-METHYL-
CHEMBL39493
Benzenemethanamine, 2,3-dichloro-alpha-methyl-
DTXSID10960000
2,3-Dichloro-alpha-methylbenzylamine hydrochloride
(R)-1-(2,3-dichlorophenyl)ethanamine
Lopac0_000476
SCHEMBL158333
CZJMQTZQSNUDNV-UHFFFAOYSA-N
DTXCID301008131
PBA22694
BDBM50100952
MFCD06654499
MFCD06762080
MFCD06762081
1-(2,3-Dichloro-phenyl)-ethylamine
AKOS012085554
CCG-204567
SDCCGSBI-0050460.P002
(S)-1-(2,3-Dichlorophenyl)ethanamine
(RS)-1-(2,3-dichlorophenyl)ethylamine
NCGC00015303-02
NCGC00015303-03
NCGC00015303-05
NCGC00162166-01
BS-52006
PD034400
SY187939
SY384747
SY384748
DB-300358
EN300-80287
(+)-2,3-Dichloro-alphamethylbenzenemethanamine
Y11085
A901232
Z1020772524
39960-84-4