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Diethylcarbamazine

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Identification
Molecular formula
C10H21N3O
CAS number
90-89-1
IUPAC name
1-[2-(diethylamino)ethyl]-1-isopentyl-3,3-diisopropyl-urea
State
State

Diethylcarbamazine is a solid at room temperature and is commonly used in the form of its citrate salt for pharmaceutical applications.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
267.44g/mol
Molar mass
267.4400g/mol
Density
1.0059g/cm3
Appearence

Diethylcarbamazine is typically found as a white, crystalline powder. It may also be available in the form of tablets or syrup, often combined with other substances for medicinal purposes.

Comment on solubility

Solubility of 1-[2-(diethylamino)ethyl]-1-isopentyl-3,3-diisopropyl-urea

The solubility of the compound 1-[2-(diethylamino)ethyl]-1-isopentyl-3,3-diisopropyl-urea (C10H21N3O) is influenced by several factors due to its complex structure and functional groups. Understanding its solubility can aid in various applications and formulations, as solubility plays a crucial role in chemical processes.

Factors Influencing Solubility:

  • Polarity: The presence of the urea group introduces some polar characteristics, which can enhance solubility in polar solvents. However, the bulky side chains may hinder full solvation.
  • Hydrogen Bonding: The ability of the urea moiety to participate in hydrogen bonding can increase solubility in water and other hydrogen-bonding solvents, thus promoting interactions with solvent molecules.
  • Chain Length: The diethylamino and isopentyl moieties contribute to a more hydrophobic nature of the compound, potentially lowering its solubility in polar solvents, while enhancing solubility in non-polar solvents.

As a result, the solubility profile of this compound is likely to show variability depending on the solvent used. In general:

  • Higher solubility may be expected in organic solvents, such as diethyl ether or dichloromethane, due to the hydrophobic character of the compound.
  • Moderate solubility could be observed in polar solvents like methanol and ethanol, influenced by hydrogen bonding interactions.
  • Minimal solubility might be encountered in water due to the competing influences of hydrophobic side groups against the urea’s polar nature.

Thus, this compound presents an interesting case of solubility dynamics arising from both its polar and non-polar characteristics, making it a subject of interest in fields such as pharmaceutical chemistry and material science.

Interesting facts

Interesting Facts about 1-[2-(diethylamino)ethyl]-1-isopentyl-3,3-diisopropyl-urea

1-[2-(diethylamino)ethyl]-1-isopentyl-3,3-diisopropyl-urea is a fascinating compound that plays a significant role in various fields of chemistry and pharmacology. Here are some notable aspects of this molecule:

  • Structure and Function: This compound features a unique molecular structure with multiple functional groups, such as the urea moiety, which is known for its biological significance. Ureas are often involved in the formation of hydrogen bonds, influencing their interactions in biological systems.
  • Biological Activity: Compounds like this urea derivative are studied for their potential as pharmaceutical agents. They may exhibit various activities, including antimicrobial and analgesic properties.
  • Dialkylamino Group: The presence of a diethylamino group is particularly interesting. Such substituents are known to enhance lipid solubility, potentially improving the compound’s ability to cross biological membranes and interact with target sites.
  • Synthesis Exploration: The synthetic pathways to create this compound can offer insights into developing new drugs. Chemists often explore innovative methods to synthesize complex molecules, highlighting the intersection of creativity and precision in organic chemistry.
  • Potential Applications: Beyond medicinal chemistry, this compound could find applications in agrochemicals or as a surfactant in various formulations. The versatility of urea compounds widens their scope for practical applications.

As researchers continue to delve into the properties and applications of 1-[2-(diethylamino)ethyl]-1-isopentyl-3,3-diisopropyl-urea, the potential for groundbreaking discoveries remains high. In the words of famous chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” Exploring such compounds certainly gives rise to a multitude of possibilities!

Synonyms
N,N-Diisopropyl-N'-isoamyl-N'-diethylaminoethylurea
54-54-6
33Y29OWS6X
N,N-diisopropyl-N'-isopentyl-N'-diethylaminoethylurea
P-286 (Pharmaceutical)
UNII-33Y29OWS6X
N-(2-(Diethylamino)ethyl)-N-(3-methylbutyl)-N',N'-bis(1-methylethyl)urea
DTXSID00202305
PNRXGUVIQVEQMN-UHFFFAOYSA-N
1-[2-(diethylamino)ethyl]-1-(3-methylbutyl)-3,3-di(propan-2-yl)urea
Q27256301
N,N-DIISOPROPYL-N'-ISOAMYL-N'-(DIETHYLAMINOETHYL)UREA
UREA, 1-(2-(DIETHYLAMINO)ETHYL)-1-ISOPENTYL-3,3-DIISOPROPYL-
UREA, N-(2-(DIETHYLAMINO)ETHYL)-N-(3-METHYLBUTYL)-N',N'-BIS(1-METHYLETHYL)-