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Propranolol

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Identification
Molecular formula
C16H21NO3
CAS number
525-66-6
IUPAC name
1-(2-allyloxyphenoxy)-3-(isopropylamino)propan-2-ol
State
State

At room temperature, Propranolol is in a solid state. It is typically provided as a tablet or capsule for administration.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.15
Boiling point (Celsius)
399.15
Boiling point (Kelvin)
672.30
General information
Molecular weight
295.39g/mol
Molar mass
295.3880g/mol
Density
1.0600g/cm3
Appearence

Propranolol is a white to off-white crystalline powder with relatively high solubility in water. It is often available in tablet or capsule form for medical applications.

Comment on solubility

Solubility of 1-(2-allyloxyphenoxy)-3-(isopropylamino)propan-2-ol

The solubility of the compound 1-(2-allyloxyphenoxy)-3-(isopropylamino)propan-2-ol (C16H21NO3) can be quite intriguing due to its unique structure and functional groups. This compound features both a hydrophobic aromatic group and hydrophilic alcohol and amine functionalities, which can influence its solubility in different environments.

Factors Influencing Solubility

Several factors play a significant role in determining the solubility:

  • Polarity: The presence of hydroxyl (–OH) and amine (–NH) groups usually enhances solubility in polar solvents such as water.
  • Hydrophobic Characteristics: The allyloxyphenyl group contributes a hydrophobic character, which may limit solubility in water but can enhance it in organic solvents.
  • Temperature: Generally, solubility increases with temperature, allowing for a greater solvation process.

In essence, this compound may exhibit:

  • Good Solubility: In polar solvents due to its hydrophilic groups.
  • Limited Solubility: In non-polar solvents because of the bulky aromatic and aliphatic segments.

As a result, when considering the solubility of 1-(2-allyloxyphenoxy)-3-(isopropylamino)propan-2-ol, it’s important to evaluate the solvent environment. The balance of hydrophobic and hydrophilic properties creates an interesting profile, making this compound suitable for various applications depending on its solubility in different types of media.

Interesting facts

Interesting Facts about 1-(2-allyloxyphenoxy)-3-(isopropylamino)propan-2-ol

This compound, known for its complex structure and unique interactions, belongs to a class of organic compounds that exhibit notable biological activity. It serves as a fascinating example of how small changes in molecular composition can lead to different properties and functionalities.

Key Features of the Compound:

  • Allyloxy and Phenoxy Groups: The presence of allyloxy and phenoxy groups enhances both its solubility and reactivity, making it a potential candidate for various chemical reactions.
  • Biological Relevance: Compounds like this one often play crucial roles in pharmacology, particularly in developing drugs that target specific receptors in the body.
  • Amine Functionalities: The isopropylamino portion contributes to the compound's ability to interact with biological systems, which could lead to interesting applications in medicinal chemistry.

Moreover, the compound's asymmetric structure allows for the potential development of enantiomerically pure forms, which can vastly differ in their biological activity. As a result, it provides a rich area for research and exploration in chiral chemistry.

As with many compounds containing multiple functional groups, the study of 1-(2-allyloxyphenoxy)-3-(isopropylamino)propan-2-ol demands a multifaceted approach, involving aspects of organic synthesis, pharmacodynamics, and structure-activity relationships. In the words of many researchers, "the design of new compounds is limited only by our imagination and understanding of chemical interactions."


This compound is not just a molecule; it represents a bridge between structure and function, opening doors to innovations in both materials science and medicine.

Synonyms
oxprenolol
6452-71-7
dl-Oxprenolol
Coretal
(+-)-Oxprenolol
Osprenololo [DCIT]
Oxprenololum
Oxprenololum [INN-Latin]
Osprenololo
Trasacor
Oxprenolol, dl-
Oxprenolol [INN:BAN]
Oxprenolol (TN)
Oxprenolol (INN)
1-(o-(Allyloxy)phenoxy)-3-(isopropylamino)-2-propanol
1-(Isopropylamino)-2-hydroxy-3-(o-(allyloxy)phenoxy)propane
CCRIS 4201
(1)-1-(o-(Allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol
EINECS 229-257-9
EINECS 245-359-6
2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-
519MXN9YZR
1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol
(+/-)-oxprenolol
1-((1-Methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-2-propanol
2-Propanol, 1-(2-allyloxyphenoxy)-3-(isopropylamino)-
OXPRENOLOL [MI]
OXPRENOLOL [INN]
CHEMBL546
2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-
OXPRENOLOL [WHO-DD]
DTXSID1043835
1-[(1-Methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-2-propanol
{2-hydroxy-3-[2-(prop-2-en-1-yloxy)phenoxy]propyl}(propan-2-yl)amine
Oxprenololum (INN-Latin)
1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol
(+)-1-(o-(Allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol
1-(Isopropylamino)-2-hydroxy-3-[o-(allyloxy)phenoxy]propane
2-PROPANOL, 1-(O-ALLYLOXYPHENOXY)-3-ISOPROPYLAMINO-
dl-Alprenolol
Trasicor 80
Coretal (*hydrochloride*)
Laracor (*hydrochloride*)
UNII-519MXN9YZR
Trasacor (*hydrochloride*)
Trasicor (*hydrochloride*)
oxprenololo
Slow-Pren (*hydrochloride*)
(2-hydroxy-3-(2-(prop-2-en-1-yloxy)phenoxy)propyl)(propan-2-yl)amine
()-Oxprenolol
1-[2-(Allyloxy)phenoxy]-3-(isopropylamino)-2-propanol
Oxprenolol Ba 39089 (*hydrochloride*)
Prestwick0_001057
Prestwick1_001057
Prestwick2_001057
Prestwick3_001057
SCHEMBL16310
BSPBio_001014
SPBio_002937
BPBio1_001116
GTPL7255
DTXCID9023835
CHEBI:91704
HY-B1486A
C07AA02
BDBM50240370
DB01580
DA-56516
AB00514712
CS-0013720
NS00000536
D08318
2Propanol, 1(2allyloxyphenoxy)3(isopropylamino)
AB00514712_07
EN300-18552821
L013416
Q425963
1-(2-allyloxyphenoxy)-3-(iso-propylamino)-2-propanol
1-(2-allyloxyphenoxy)-3-(isopropylamino)propan-2-ol
BRD-A43671941-003-03-6
BRD-A43671941-003-11-9
1-(2-(allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol
1-[2-(Allyloxy)phenoxy]-3-(isopropylamino)-2-propanol #
1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)-2-propanol
2Propanol, 1((1methylethyl)amino)3(2(2propenyloxy)phenoxy)
1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol (Oxprenolol)
1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol(oxprenolol)
1-[2-(prop-2-en-1-yloxy)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol
2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-, (+/-)
229-257-9