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Tuberculosis Nucleoside Tubercidin

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Identification
Molecular formula
C12H15N5O2
CAS number
69-72-7
IUPAC name
1-[2-[(4-aminobenzoyl)amino]acetyl]-N-[1-[[2-(hydroxyamino)-1-methyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]pyrrolidine-2-carboxamide
State
State

At room temperature, Tuberculosis Nucleoside Tubercidin is in a solid state.

Melting point (Celsius)
288.00
Melting point (Kelvin)
561.15
Boiling point (Celsius)
812.00
Boiling point (Kelvin)
1 085.15
General information
Molecular weight
268.02g/mol
Molar mass
268.2710g/mol
Density
1.5700g/cm3
Appearence

Tuberculosis Nucleoside Tubercidin typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility Characteristics of 1-[2-[(4-Aminobenzoyl)amino]acetyl]-N-[1-[[2-(hydroxyamino)-1-methyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]pyrrolidine-2-carboxamide

The solubility of the compound with the formula C12H15N5O2 can be influenced by its intricate molecular structure and the various functional groups present. Understanding its solubility is crucial for determining its suitability in different applications. Here are some key points:

  • Hydrophilic and Hydrophobic Balance: The presence of amino and carbamoyl groups suggests that this compound may exhibit significant hydrophilicity, which could enhance solubility in polar solvents.
  • Effect of Functional Groups: The hydroxyamino and amino functional groups are known to increase solubility in aqueous environments due to their ability to form hydrogen bonds.
  • Non-Polar Components: The presence of certain hydrophobic regions, such as the phenyl ring from the 4-aminobenzoyl group, may limit overall solubility in non-polar solvents.
  • Solvent Dependency: Solubility can vary significantly depending on the choice of solvent, and it is likely to be more soluble in water or alcohols compared to non-polar solvents.

In summary, while the compound may be moderately soluble in polar solvents due to its hydrophilic functional groups, its overall solubility profile will depend greatly on the specific conditions and solvents used. As such, conducting systematic solubility tests across a range of environments would yield more precise data for this complex molecule.

Interesting facts

Interesting Facts about 1-[2-[(4-aminobenzoyl)amino]acetyl]-N-[1-[[2-(hydroxyamino)-1-methyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]pyrrolidine-2-carboxamide

This remarkable compound, often referred to for its intricate structure and various applications in the field of medicinal chemistry, showcases a fascinating interplay of functional groups that contribute to its biological activity. Here are some engaging aspects:

  • Complex Structure: The compound features multiple amine and carbonyl groups that significantly affect its reactivity and interaction with biological systems.
  • Biological Relevance: Due to its structural characteristics, it has been investigated for potential use in treating various diseases, especially cancer, as the presence of an aminobenzoyl moiety is often linked to pharmacophores in anticancer agents.
  • Synthetic Challenges: The synthesis of this compound involves a range of organic reactions, which can be challenging yet rewarding for chemists. Techniques such as acylation and the formation of complex amide bonds are crucial in its preparation.
  • Potential Applications: Beyond its relevance in cancer treatment, compounds with similar structural motifs have been explored for antibiotic properties and as enzyme inhibitors.

As chemists explore this compound further, it’s intriguing to think about the potential pathways it could lead to in the development of new therapeutics. With each modification, the properties of such compounds may yield exciting discoveries.

"In the world of chemistry, complexity often leads to remarkable solutions." - An inspiring mantra for aspiring chemists.

Overall, the study of this compound emphasizes the *importance of structure-activity relationships* in drug design, making it a significant subject of research.

Synonyms
MMP Inhibitor I
4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH
FN-439
DTXSID40274440
FA111048