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Tryptamine

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Identification
Molecular formula
C10H12N2
CAS number
61-54-1
IUPAC name
1-(1H-indol-3-yl)propan-2-amine
State
State

Tryptamine is typically found in solid form at room temperature. It is a crystalline substance and can be easily handled as a powder or solid.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
140.00
Boiling point (Kelvin)
413.15
General information
Molecular weight
160.22g/mol
Molar mass
160.2240g/mol
Density
1.2000g/cm3
Appearence

Tryptamine appears as a white to off-white crystalline solid. It is known for its crystalline nature which can sometimes appear slightly shiny or dull depending on purity and handling.

Comment on solubility

Solubility of 1-(1H-indol-3-yl)propan-2-amine

The solubility of 1-(1H-indol-3-yl)propan-2-amine, often referred to as a pharmacologically relevant indole derivative, plays a significant role in its biological activity and application. Understanding its solubility characteristics is essential for effective formulation and delivery in pharmaceutical contexts. Here are some important aspects to consider:

  • Solvent Types: This compound exhibits varying solubility in different solvents, with a notable tendency to dissolve in polar solvents such as water, methanol, and ethanol, but showing limited solubility in non-polar solvents.
  • Temperature Effects: Solubility generally increases with temperature, which can be leveraged in specific formulation processes.
  • pH Dependency: The ionization of the amine group may significantly influence solubility; therefore, adjusting the pH can enhance its dissolve characteristics in aqueous solutions.
  • Crystalline vs. Amorphous Forms: The solid-state form of the compound can also affect solubility, with amorphous forms often displaying higher solubility than crystalline forms.

In summary, the solubility of 1-(1H-indol-3-yl)propan-2-amine is a multifaceted property influenced by various factors such as solvent characteristics, temperature, pH, and physical state. For optimal use, understanding and manipulating these factors is critical to harnessing its full potential in biochemical applications.

Interesting facts

Interesting Facts About 1-(1H-indol-3-yl)propan-2-amine

1-(1H-indol-3-yl)propan-2-amine, commonly referred to within the realm of research as an *amine derivative*, presents a fascinating profile in the study of various biological activities. This compound is notable for several reasons:

  • Indole Framework: The compound features an indole structure, which is a significant building block in medicinal chemistry. Indoles are known for their prevalence in many natural products and pharmaceutical agents.
  • Psychoactive Properties: There has been research into compounds similar to 1-(1H-indol-3-yl)propan-2-amine for their psychoactive properties. Understanding its interaction with neurotransmitter systems can provide insights into potential therapeutic applications.
  • Use in Research: This compound is often utilized as a reference standard in instructive studies exploring the interactions of indole derivatives with various receptors, particularly the serotonin receptors, which are crucial in mood regulation and anxiety control.
  • Structural Analogues: Interest in this compound has spurred studies into its analogues that might offer improved activity or reduced side effects, demonstrating the delicate balance between structure and function in drug design.

The study of compounds like 1-(1H-indol-3-yl)propan-2-amine emphasizes the intricate relationship between chemical structure and biological function. As researchers delve into the pharmacological potential of such compounds, the insights gained can lead to the development of novel therapeutic agents with significant benefits for mental health and beyond.

"Every molecule tells a story; it's up to us to decode it." This sentiment resonates deeply within the scientific community as we continue our quest for knowledge and understanding.

Synonyms
alpha-Methyltryptamine
Indopan
3-(2-Aminopropyl)indole
299-26-3
1-(1H-indol-3-yl)propan-2-amine
alpha-Methyl-beta-indoleethylamine
DL-3-(2-Aminopropyl)indole
1-(1H-Indol-3-yl)-2-propanamine
alpha-Methyl-1H-indole-3-ethanamine
alpha-Methyl-3-indoleethanamine
INDOLE, 3-(2-AMINOPROPYL)-
Ro 3-0926
.alpha.-Methyltryptamine
IT-403(D)
DL-alpha-Methyltryptamine
(+-)-alpha-Methyltryptamine
U 14164 E
NSC 97069
Spirals [Street Name]
alphaMT
alpha-Methyl-beta-indolaethylamine
BIK35ACJ0Q
1H-Indole-3-ethanamine, .alpha.-methyl-
IT-290(D,L)
EINECS 206-073-7
U-14164E(D,L)
.alpha.-Methyl-.beta.-indoleethylamine
1H-Indole-3-ethanamine, alpha-methyl-
BRN 0140457
SPIRALS
164E
U 14
CHEBI:59020
alpha-Methyl-beta-indolaethylamine [German]
.alpha.-Methyl-3-indoleethanamine
164 E
.ALPHA.MT
NSC-97069
It-290(dl)
2-(1H-indol-3-yl)-1-methylethylamine
u-14164e(dl)
CHEMBL30713
(+/-)-alpha-methyltryptamine
.ALPHA.-METHYLTRYPTAMINE-
DL-.ALPHA.-METHYLTRYPTAMINE
5-22-10-00144 (Beilstein Handbook Reference)
.ALPHA.-METHYLTRYPTAMINE [MI]
DL-alfa-methyltryptamine
3-(2-AMINOPROPYL)-1H-INDOLE
(+/-)-.ALPHA.-METHYLTRYPTAMINE
Spirals (Street Name)
1H-Indole-3-ethanamine, alpha-methyl- (9CI)
304-54-1
U 14 (VAN)
UNII-BIK35ACJ0Q
(+-)-alpha-Methyl-1H-indole-3-ethanamine
INDOLE, 3-(2-AMINOPROPYL)-, (+-)-
a-methyl tryptamine
alpha-Methyl tryptamine
AMT-
Tryptamine, .alpha.-methyl
1H-Indole-3-ethanamine, alpha-methyl-, (+-)-
Oprea1_004262
alpha-Methyltryptamine, 99%
ALPHA-METHYLTRYPTAMINE-
SCHEMBL274268
DEA No. 7432
WLN: T56 BMJ D1YZ1
DTXSID00861850
NSC97069
BDBM50014210
DL-alpha-Methyltryptamine, free base
MFCD00005654
PDSP1_000039
PDSP1_000947
PDSP2_000039
PDSP2_000933
STK926814
AKOS000276077
AKOS016041665
.alpha.-methyl-.beta.-indolaethylamine
DB01446
1-(1H-Indol-3-yl)-2-propanamine #
1H-Indole-3-ethanamine, .alpha.-methyl
NCGC00332100-01
NCGC00332100-02
2-(1H-Indol-3-yl)-1-methyl-ethylamine
AC-28321
[2-(1H-indol-3-yl)-1-methylethyl]amine
DB-006231
NS00017916
1H-Indole-3-ethanamine, alpha-methyl-(9CI)
rac. 2-(1H-indol-3-yl)-1-methylethylamine
C20127
M-4620
AB01325935-02
Q421163
206-073-7