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Tryptamine

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Identification
Molecular formula
C10H12N2
CAS number
61-54-1
IUPAC name
1-(1H-indol-3-yl)-N,N-dimethyl-methanamine
State
State

At room temperature, tryptamine is typically found in a solid state. It is crystalline in nature and is often handled in its solid form for various applications, including research and synthesis.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
378.00
Boiling point (Kelvin)
651.15
General information
Molecular weight
160.22g/mol
Molar mass
160.2270g/mol
Density
1.1873g/cm3
Appearence

Tryptamine is a white to slightly yellow crystalline solid. It may appear as small white crystals when purified, but can develop a slight yellowish tint upon exposure to air or due to impurities.

Comment on solubility

Solubility of 1-(1H-indol-3-yl)-N,N-dimethyl-methanamine

1-(1H-indol-3-yl)-N,N-dimethyl-methanamine is a compound with fascinating solubility characteristics that can be influenced by several factors. Here are some key points to consider:

  • Polarity: The presence of an indole moiety contributes to a certain degree of polarity, which can affect its solubility in polar solvents.
  • Solvent Compatibility: This compound is likely to be more soluble in polar organic solvents such as dichloromethane or ethanol compared to non-polar solvents.
  • Hydrogen Bonding: The amine group may partake in hydrogen bonding, enhancing its solubility in protic solvents.
  • Concentration Effects: At higher concentrations, interactions between molecules may cause decreased solubility due to aggregation or precipitation.

Overall, the solubility of 1-(1H-indol-3-yl)-N,N-dimethyl-methanamine can be summarized by the following quote: "Solubility is not merely a property of the solute but also of the medium that surrounds it." Thus, when considering its application or use in various environments, understanding the context of solubility becomes essential.

Interesting facts

Facts About 1-(1H-indol-3-yl)-N,N-dimethyl-methanamine

1-(1H-indol-3-yl)-N,N-dimethyl-methanamine, often referred to as a derivative of indole, is a fascinating compound due to its structural complexity and potential applications in various fields. Here are some interesting insights about this compound:

  • Indole Backbone: This compound features an indole moiety, which is a heterocyclic compound composed of a benzene ring fused to a pyrrole ring. Indoles are well-known for their presence in many biologically active molecules, including neurotransmitters and natural products.
  • Psychoactive Properties: Compounds related to the indole structure, including tryptamines, are often associated with psychoactive effects. The presence of the dimethylamino group in this compound may influence its interaction with the nervous system.
  • Synthesis: The synthesis of this compound can be achieved through various organic reactions, offering a valuable opportunity for chemists to explore different synthetic routes and methodologies in the laboratory.
  • Potential Biological Activity: Many indole derivatives are studied for their pharmacological properties. Research indicates that they may exhibit a variety of activities, including anticancer, antimicrobial, and anti-inflammatory effects, which makes them of great interest in medicinal chemistry.
  • Research Applications: This compound's unique structure allows it to be used in a wide array of research applications, particularly in the development of pharmaceuticals and as a building block in organic synthesis.

As a compound replete with potential, 1-(1H-indol-3-yl)-N,N-dimethyl-methanamine serves as a prime example of how structural modifications can lead to a diverse range of properties and applications in chemistry and beyond!

Synonyms
Gramine
87-52-5
3-(Dimethylaminomethyl)indole
Donaxine
Donaxin
Gramin
1-(1H-indol-3-yl)-N,N-dimethylmethanamine
1H-Indole-3-methanamine, N,N-dimethyl-
beta-Dimethylaminomethylindole
Indol-3-ylmethyldimethylamine
NSC 16892
(1H-Indol-3-ylmethyl)-dimethyl-amine
3-[(Dimethylamino)methyl]indole
3-(N,N-Dimethylaminomethyl)indole
MFCD00005629
N,N-Dimethyl-1H-indole-3-methanamine
(Indol-3-ylmethyl)dimethylamine
(1H-indol-3-ylmethyl)dimethylamine
EINECS 201-749-8
Indole, 3-[(dimethylamino)methyl]-
UNII-FGQ8A78L14
FGQ8A78L14
.beta.-Dimethylaminomethylindole
AI3-52146
GRAMINE [MI]
NSC-16892
N,N-Dimethyl-1H-indole-3-methylamine
3-[Dimethylaminomethyl]indole
INDOLE, 3-((DIMETHYLAMINO)METHYL)-
beta-(Dimethylaminomethyl)indole
DTXSID3058955
CHEBI:28948
[(1H-indol-3-yl)methyl]dimethylamine
3-((DIMETHYLAMINO)METHYL)INDOLE
(1H-indol-3-yl)-N,N-dimethylmethanamine
.BETA.-(DIMETHYLAMINOMETHYL)INDOLE
3-((Dimethylamino)methyl)-Indole
3-[(Dimethylamino)methyl]-Indole
1-(1H-indol-3-yl)-N,N-dimethyl-methanamine
Prestwick_245
Gramine (Standard)
Gramine, 99%
Enamine_005691
Prestwick0_000629
Prestwick1_000629
Prestwick2_000629
Prestwick3_000629
3-((N,N-Dimethylamino)methyl)indole (Gramine)
Oprea1_150946
SCHEMBL63578
b-(Dimethylaminomethyl)indole
BSPBio_000598
MLS002153919
beta -dimethylaminomethylindole
SCHEMBL445889
SPBio_002817
indole, 3-dimethylaminomethyl-
BPBio1_000658
CHEMBL254348
DTXCID5048552
HY-N0166R
HMS1410C15
HMS1569N20
HMS2096N20
HMS2268O03
HMS3651E18
3-Dimethylaminomethylindol (gramin)
HY-N0166
NSC16892
TNP00029
WLN: T56 BMJ D1N1&1
CCG-46378
HB0305
s2304
STL146344
(1H-Indol-3-ylmethyl)-dimethylamine
AKOS001055234
FG39390
1H-Indol-3-yl-N,N-dimethylmethanamine
CAS-87-52-5
IDI1_007926
NCGC00016343-01
NCGC00016343-02
NCGC00016343-03
NCGC00016343-04
NCGC00016343-05
NCGC00016343-13
NCGC00142364-01
NCGC00142364-02
NCGC00142364-03
AC-15584
AS-11847
SMR000112262
SY005107
1H-Indol-3-yl-N,N-dimethylmethanamine #
DB-057006
CS-0007885
D0653
N,N-Dimethyl-1H-indole-3-methanamine, 9CI
NS00039200
SW196552-2
EN300-05999
C08304
AE-508/21133004
AE-641/04280037
Q420118
SR-01000636080
SR-01000636080-1
SR-01000636080-4
BRD-K26005076-001-03-7
BRD-K26005076-001-06-0
BRD-K26005076-001-12-8
Z56917380