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Alpha-Methyltryptamine

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Identification
Molecular formula
C11H14N2
CAS number
299-26-3
IUPAC name
1-(1H-indol-3-yl)-2-methyl-propan-2-amine
State
State

Alpha-Methyltryptamine is generally found as a solid at room temperature. It can be in the form of a powder or crystalline solid, depending on its processing and purity level.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.15
Boiling point (Celsius)
268.50
Boiling point (Kelvin)
541.60
General information
Molecular weight
174.26g/mol
Molar mass
174.2580g/mol
Density
1.1694g/cm3
Appearence

Alpha-Methyltryptamine, commonly known as AMT, is a crystalline or powdery substance. It appears as white to off-white crystals or powder. Its appearance can vary slightly depending on its purity and form.

Comment on solubility

Solubility of 1-(1H-indol-3-yl)-2-methyl-propan-2-amine

The solubility of 1-(1H-indol-3-yl)-2-methyl-propan-2-amine, often referred to in academic and research contexts, exhibits unique characteristics due to its chemical structure. Understanding its solubility properties is crucial for various applications, particularly in pharmaceuticals and biochemistry.

Factors Influencing Solubility:

  • Polarity: The compound contains both hydrophobic (due to the indole ring) and hydrophilic (the amine group) regions, leading to variable solubility in polar and non-polar solvents.
  • Temperature: Generally, higher temperatures can increase solubility in solvents, making it essential to consider the specific conditions under which this compound is dissolved.
  • pH Levels: As an amine, its solubility can be significantly affected by the pH of the solution; it is more soluble in acidic conditions due to protonation.

In terms of general solubility:

  • In water: The solubility is limited, primarily due to the indole's aromatic nature.
  • In organic solvents: It tends to dissolve better in organic solvents like ethanol or chloroform, where the hydrophobic interactions can be better accommodated.

Overall, while 1-(1H-indol-3-yl)-2-methyl-propan-2-amine may not be readily soluble in all environments, its unique structure can be manipulated for enhanced solubility under suitable conditions. As always, exploring the specific compatibility with various solvents is key in applications where solubility plays a critical role.

Interesting facts

Interesting Facts about 1-(1H-indol-3-yl)-2-methyl-propan-2-amine

1-(1H-indol-3-yl)-2-methyl-propan-2-amine, commonly known as an indole derivative, is a fascinating compound in the realm of organic chemistry. This compound belongs to a class of chemicals characterized by the indole ring structure, which has notable implications in various biological systems.

Key Characteristics and Applications:

  • Indole Derivative: The presence of the indole ring is significant as it is often found in many natural compounds, including amino acids like tryptophan and various alkaloids.
  • Psychopharmacological Potential: Compounds featuring the indole structure have been studied extensively for their roles in neuroscience, with some analogs acting as *serotonin receptor modulators*, which may influence mood and cognition.
  • Research Interest: Researchers are increasingly interested in the compound due to its potential therapeutic effects, including antidepressant and anxiolytic properties, which can lead to new treatments for mental health disorders.

Chemical Properties:

With its specific substitution pattern, this compound may exhibit unique reactivity and binding characteristics that researchers aim to explore. The balance of *hydrophobic* and *hydrophilic* properties enhances its biochemical activity.

Safety and Handling:

As with any chemical compound, proper safety protocols must be followed when handling 1-(1H-indol-3-yl)-2-methyl-propan-2-amine. Understanding its *toxicological* profile is vital for safe laboratory practices.

In conclusion, 1-(1H-indol-3-yl)-2-methyl-propan-2-amine, with its unique structure and properties, presents an exciting opportunity for scientists, particularly in the fields of medicinal and pharmaceutical chemistry. Its exploration may lead to valuable insights and advancements in drug development.

Synonyms
1-(1H-indol-3-yl)-2-methylpropan-2-amine
304-53-0
INDOLE, 3-(2-AMINO-2-METHYLPROPYL)-
a,a-Dimethyltryptamine
alpha,alpha-Dimethyltryptamine
BRN 0127833
1H-Indole-3-ethanamine, alpha,alpha-dimethyl-
Ro 3-1638
1-(INDOL-3-YL)-2-METHYLPROPAN-2-AMINE
alpha,alpha-Dimethyl-1H-indole-3-ethanamine; 1-(1H-Indol-3-yl)-2-methylpropan-2-amine; 3-(2-Amino-2,2-dimethylethyl)indole; alpha,alpha-Dimethyl-3-indoleethanamine; Ro 3-1638
5-22-10-00183 (Beilstein Handbook Reference)
SCHEMBL4100216
DTXSID10184481
WREHPEFXXFJIIJ-UHFFFAOYSA-N
AAA30453
MFCD01719186
AKOS006277372
3-(2'-methyl-2'-aminopropyl) indole
AB09840
SS-4588
2-(3-indolyl)-1,1-dimethylethylamine
DB-016241
[2-(1H-indol-3yl)-1,1-dimethylethyl]amine
1,1-dimethyl-2-(1H-indol-3-yl)ethyl amine
[2-(1H-indol-3-yl)-1,1-dimethylethyl]amine
[2- (1H-indol-3-yl)-1,1-dimethylethyl]amine
2-(3 -INDOLYL)-1,1-DIMETHYLETHYLAMINE
EN300-1830764
800-136-8