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Enfuvirtide

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Identification
Molecular formula
C23H36N6O
CAS number
159519-65-0
IUPAC name
1-(1-adamantyl)-3-[(4-guanidinophenyl)methyl]urea
State
State

At room temperature, Enfuvirtide exists as a solid substance.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
219.31g/mol
Molar mass
219.3100g/mol
Density
1.3000g/cm3
Appearence

Enfuvirtide appears as a white to off-white powder.

Comment on solubility

Solubility of 1-(1-adamantyl)-3-[(4-guanidinophenyl)methyl]urea

The solubility of 1-(1-adamantyl)-3-[(4-guanidinophenyl)methyl]urea (C23H36N6O) presents an intriguing study due to its unique structural characteristics. This compound is a distinguished urea derivative featuring both hydrophobic adamantyl and guanidinophenyl moieties, which influence its solubility properties.

Factors Affecting Solubility

The solubility of this compound can be influenced by several key factors:

  • Polar and Nonpolar Interactions: The hydrophobic nature of the adamantyl group may limit solubility in polar solvents, while the guanidine functionality is more polar and could enhance solubility in specific polar solvents.
  • Solvent Choice: Its solubility is likely to be higher in organic solvents such as dimethyl sulfoxide (DMSO) or polar aprotic solvents compared to water.
  • Temperature: Generally, increasing temperature can enhance solubility for many compounds, and this compound may follow that trend, though explicit empirical data would be necessary to confirm this behavior.

Conclusion

Overall, the solubility of 1-(1-adamantyl)-3-[(4-guanidinophenyl)methyl]urea is a nuanced topic, reflecting the balance between its polar and nonpolar characteristics. It is essential to investigate specific conditions, as stated, to fully comprehend its solubility profile in various solvents. As with many chemical compounds, "solubility is key," determining its practical applications in fields such as pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 1-(1-adamantyl)-3-[(4-guanidinophenyl)methyl]urea

1-(1-adamantyl)-3-[(4-guanidinophenyl)methyl]urea, often referred to for its unique structure and potential applications, is an intriguing compound in the field of medicinal chemistry. Here are some fascinating insights:

  • Dual Functionality: This compound combines the characteristics of both adamantane and guanidine, providing it with unique pharmacological properties. The adamantyl group enhances membrane permeability, while the guanidine group is known for its biological activity.
  • Applications in Medicine: Compounds containing the guanidino moiety are often studied for their potential therapeutic effects, particularly in antitumor, antiviral, and antibacterial treatments.
  • Innovative Research: Researchers are investigating its role as a potential lead compound for developing new classes of drugs, especially in targeting specific enzymes or receptors in the body.
  • Synthetic Pathways: The synthesis of this compound can involve multiple steps, often requiring advanced techniques such as solid-phase synthesis or multi-component reactions, showcasing the complexity of modern organic synthesis.
  • Chemical Versatility: The presence of both urea and guanidine functional groups allows for further chemical modifications, making this compound a valuable intermediate in organic synthesis.

The study of 1-(1-adamantyl)-3-[(4-guanidinophenyl)methyl]urea not only enhances our understanding of chemical interactions but also opens up possibilities for drug development and therapeutic strategies. As research progresses, we anticipate exciting findings that will shed light on its efficacy and potential use in various biomedical fields.

Synonyms
n-(1-adamantyl)-n'-(4-guanidinobenzyl)urea
AGB
282718-42-7
3-(adamantan-1-yl)-1-((4-((diaminomethylidene)amino)phenyl)methyl)urea
3-(adamantan-1-yl)-1-({4-[(diaminomethylidene)amino]phenyl}methyl)urea
1ejn
SCHEMBL4328331
WX293T
SCHEMBL14524522
BDBM16176
DB03782
PD040821
PD059478
NS00069526
1-(Adamantan-1-yl)-3-(4-guanidinobenzyl)urea
Q27094675
3-(1-adamantyl)-1-[(4-carbamimidamidophenyl)methyl]urea
3-adamantan-1-yl-1-[(4-carbamimidamidophenyl)methyl]urea
1-(4-carbamimidamidobenzyl)-3-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]urea